Paramagnetic nuclear magnetic resonance shifts

Mao, J.H., Zhang, Y., Oldfield, E. Nuclear magnetic resonance shifts in paramagnetic metallopor-phyrins and metalloproteins. J. Am. Chem. Soc. 2002,124,13911-20. 

Mao JH, Zhang Y, Oldfield E (2002) Nuclear magnetic resonance shifts in paramagnetic metalloporphyrins and metalloproteins. J Am Chem Soc 124 13911-13920... 

The paramagnetic properties of Co(II) have been utilized in some biochemical applications of nuclear magnetic resonance. Cobalt(II)-induced contact shifts were observed in lysozyme (26). A preferential binding of Co2+ to a single site presumably involving two carboxyl groups was deduced. This technique might become very informative in studies of metal ion-dependent enzyme systems. 

Nuclear magnetic resonance (NMR) is a similar type of paramagnetic phenomenon. Like ESR, NMR involves the generation of a signal by the application of an external magnetic field, except that in NMR, shifts in the orientation of the nucleus, rather than of the unpaired electrons, are measured with respect to the external field (cf. Dyer 1965). The major point for our discussion, which would indicate that ESR rather than NMR would function as the modulated carrier-wave, is that unpaired electrons are characteristic of charge-transfer reactions and semiconduction, and as we have seen previously, serotonin and many of its analogs can function as power-... 

Nuclear magnetic resonance (NMR) Chemical shift, nuclear coupling constants, relaxation times For paramagnetic proteins enhanced chemical shift resolution, contact and dipolar shifts, spin delocalisation, magnetic coupling from temperature dependence of shifts. 

In solutions, nuclear magnetic resonance is of use from the H paramagnetic shift (AAv) of a reference compound, corrected for the diamagnetic contribution of the ligands, the paramagnetic susceptibility is evaluable using the Evans method [10]... 

Whereas the paramagnetic shift of the nuclear magnetic resonance frequency for a given applied field is related to the strength of the local hyperfine field at the nuclear site, induced by the electronic moments, the nuclear spin-lattice relaxation rate yields information about the low-frequency spectrum of thermally induced spin fluctuations. The influence of pair-correlation effects on the NMR relaxation in paramagnets was analysed experimentally and theoretically by... 

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