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Paclitaxel, polymer formulation containing

The polymer formulations containing anticancer agents (paclitaxel and cis-platin) were evaluated in vivo in heterotrophic (mouse bladder tumor) and orphotrophic (rat prostate cancer) models. Single administration of polymer-pactlitaxel formulation intratumorally in a mouse bladder tumor model increased the survival rate of the animals compared to untreated animals and to animals treated with paclitaxel dispersion (conventional administration method) (27). The optimal load of paclitaxel in the polymer was established as 10% w/w. Mice treated with this formulation showed median survival rate (MSR) of... [Pg.93]


See other pages where Paclitaxel, polymer formulation containing is mentioned: [Pg.93]    [Pg.325]    [Pg.497]    [Pg.65]    [Pg.51]    [Pg.293]    [Pg.288]    [Pg.490]    [Pg.76]    [Pg.93]    [Pg.94]    [Pg.62]    [Pg.27]    [Pg.310]    [Pg.273]    [Pg.27]    [Pg.1731]   
See also in sourсe #XX -- [ Pg.65 ]

See also in sourсe #XX -- [ Pg.65 ]




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Paclitaxel, polymer formulation

Paclitaxels

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