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Paclitaxel Methotrexate

Carcinomas of head and neck Fluorouracil plus cisplatin, cisplatin plus paclitaxel Methotrexate, bleomycin, hydroxyurea, doxorubicin, vincristine, vinorelbine... [Pg.1311]

Additional polyesters were synthesized by the polycondensation of lactic acid and castor oil (Figure 5) and examined as injectable controlled delivery carriers for cytotoxic drugs (paclitaxel, methotrexate, 5FU and cis-platin). [Pg.95]

Cyclophosphamide 600 mg/m2 IV, day 1 Methotrexate 40 mg/m2 IV, day 1 Fluorouracil 600 mg/m2 IV, days 1 and 8 Repeat cycles every 28 days for 6 cycles Dose-dense AC —> paclitaxel Doxorubicin 60 mg/m2 IV bolus, day 1 Cyclophosphamide 600 mg/m2 IV, day 1 Repeat cycles every 14 days for 4 cycles (must be given with growth factor support) Followed by ... [Pg.1311]

AC, Adriamycin (doxorubicin), Cytoxan (cyclophosphamide) CAF, Cytoxan (cyclophosphamide), Adriamycin (doxorubicin), 5-fluorouracil CEF, cyclophosphamide, epirubicin, 5-fluorouracil CMF, cyclophosphamide, methotrexate, 5-flourouracil FAC, 5-fluorouracil, Adriamycin (doxorubicin), cyclophosphamide FEC, 5-fluorouracil, epirubicin, cyclophosphamide TAC, Taxol (paclitaxel), Adriamycin (doxorubicin), cyclophosphamide. [Pg.697]

Anticancer drugs Methotrexate Doxorubicin Daunorubicin Epirubicin Etoposide Vincristine Vinblastine Paclitaxel Iiinotecan... [Pg.44]

A randomized phase II trial comparing weekly methotrexate (MTX, 40-60 mg/m2) vs triweekly paclitaxel (175-225 mg/m2 by 3-h or 24-h infusion) in the recurrent or metastatic setting was prematurely closed as a result of toxicity and minimal response (76). [Pg.163]

Vermorken J, Catimel G, Mulder PD, et al. Randomized phase II trial of weekly methotrexate (MTX) versus two schedules of triweekly paclitaxel (taxol) in patients with metastatic or recurrent squamous cell carcinoma of the head and neck (SCCHN). ProcAnnu Meet Am Soc Clin Oncol 1999 18 A 1527. [Pg.173]

Most anticancer drugs damage hair follicles and produce partial or complete alopecia. Patients should be warned of this reaction, especially if paclitaxel, cyclophosphamide, doxorubicin, vincristine, methotrexate, or dactinomycin is used. Hair usually regrows normally after completion of chemotherapy. [Pg.634]

Carcinoma of breast (1) Adjuvant chemotherapy or tamoxifen after primary breast surgery Cyclophosphamide, doxorubicin, vincristine, methotrexate, fluorouracil, paclitaxel, mitoxantrone, prednisone, megestrol, androgens,1 aminoglutethimide, trastuzumab... [Pg.1311]

Fig. 3 Venn-diagram for selected compounds interacting with the key MDR-related ABC transporters. MDR-substrate anticancer agents. Abbreviations VCR vincristine, VP-16 etoposide, STER steroids, TAM tamoxiphen, TKI-INHIB tyrosin kinase inhibitors e.g. STI-571, DOX doxorubicine or adriamycin, DNR daunorubicin, EPIR epirubicin, MX mitoxantrone, TOPOT topotecan, iridotecan, BISANT bisanthrone, COLCH colchicin, ACT-D actinomycin D, MYTOM mytomycin, TX methotrexate, CPHAM cyclophosphamide, CHLB chlorambucil, CARM carmustine, LCV leucovorin, HUR hydroxy urea, CISPL cisplatin, TAXOL paclitaxel. (Reproduced from [4])... Fig. 3 Venn-diagram for selected compounds interacting with the key MDR-related ABC transporters. MDR-substrate anticancer agents. Abbreviations VCR vincristine, VP-16 etoposide, STER steroids, TAM tamoxiphen, TKI-INHIB tyrosin kinase inhibitors e.g. STI-571, DOX doxorubicine or adriamycin, DNR daunorubicin, EPIR epirubicin, MX mitoxantrone, TOPOT topotecan, iridotecan, BISANT bisanthrone, COLCH colchicin, ACT-D actinomycin D, MYTOM mytomycin, TX methotrexate, CPHAM cyclophosphamide, CHLB chlorambucil, CARM carmustine, LCV leucovorin, HUR hydroxy urea, CISPL cisplatin, TAXOL paclitaxel. (Reproduced from [4])...
Docetaxel Etoposide Eluorouracil Gemcitabine Methotrexate Mitomycin Mitoxantrone Paclitaxel Pemetrexed Topotecan Trastuzumab Bevacizumab Bleomycin Busulfan... [Pg.296]

Fluorouracil Glucocorticoids Indinavir Loperamide Losartan Methotrexate Mitoxantrone Nelfinavir Paclitaxel Ritonavir Saquinavir Sirolimus Tacrolimus Topotecan Vinblastine Vincristine Vindesine Vinorelbine Verapamil ... [Pg.631]

Cytotoxic drags that have been used alone and in combination as adjuvant therapy in breast cancer include doxorubicin, epirubicin, cyclophosphamide, methotrexate, fluorouracil, paclitaxel, docetaxel, melphalan, prednisone, vinorelbine, and vincristine. The most common combination chemotherapy regimens employed in the adjuvant and metastatic setting are listed in Table 125-11. [Pg.2347]

SLC01B3 OATP8 Bile salts, organic anions Digoxin, methotrexate, rifampin, paclitaxel Liver, cancer cell lines Hagenbuch and Meier,... [Pg.120]

ABCCl MRPl Camptothecins, colchicine, daunorubicin, doxorubicin, etoposide, methotrexate, paclitaxel, vincristine, vinblastine... [Pg.124]

An in vitro study in human bladder cancer cells found that the antineoplas-tic effect of paclitaxel in combination with methotrexate was dependent on the order of exposure to the two drugs. ... [Pg.663]

Cos J, Bellmunt J, Soler C, Ribas A, Lluis JM, Murio JE, Margarit C. Comparative study of sequential combinations of paclitaxel and methotrexate on a human bladder cancer cell line Cancer Invest (2000) 18, 429-35. [Pg.663]

See other pages where Paclitaxel Methotrexate is mentioned: [Pg.130]    [Pg.526]    [Pg.130]    [Pg.526]    [Pg.1319]    [Pg.96]    [Pg.100]    [Pg.377]    [Pg.52]    [Pg.709]    [Pg.712]    [Pg.78]    [Pg.87]    [Pg.91]    [Pg.456]    [Pg.1318]    [Pg.361]    [Pg.541]    [Pg.385]    [Pg.87]    [Pg.91]    [Pg.496]    [Pg.391]    [Pg.395]    [Pg.2356]    [Pg.2378]    [Pg.2476]    [Pg.55]    [Pg.1163]    [Pg.124]    [Pg.331]    [Pg.490]    [Pg.248]    [Pg.419]   
See also in sourсe #XX -- [ Pg.663 ]



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