Packing of a helices

Chofhia, C., Levitt, M., Richardson, D. Structure of proteins packing of a-helices and pleated sheets. 

Crick, F.H.C. The packing of a-helices simple coiled coils. Acta Cryst. 6 689-697, 1953. 

Richmond, T.J., Richards, EM. Packing of a-helices geometrical constraints and contact areas. /. Mol. Biol. 119 537-555, 1978. 

Cohen, F.E., Sternberg, M.J.E., Taylor, W.R, Analysis and prediction of the packing of a-helices against a p-sheet in the tertiary structure of globular proteins. 

Crick, F. H. C. (1953b). The packing of a-helices Simple coiled-coils. Acta Crystallogr. 6, 689-697. 

N. K. Rogers and M. J. E. Sternberg,/. Mol. Biol., 174,527 (1984). Electrostatic Interactions in Globular Proteins. Different Dielectric Models Applied to the Packing of a-Helices. 

A third type of supersecondary structure results from the packing of a helices on to 0 sheets.Two parallel 0 strands form a sheet with a particular handedness. The linker between these 0 structures can either be an a helix, a coil, or another strand. By examining several protein... 

Assembly in proteins involves packing of a helices and / sheets. Together they play important roles in protein folding. Assembly of subunits gives the active protein. In spherical viruses such assembly involves identical subunits, and the symmetry found in the resulting coat is of interest. 

Efimov, A. V. Packing of a-helices in globular proteins. Layer-structure of globin hydrophobic cores. J. Molec. Biol. 134, 23-40 (1979). 

Chothia, C., Levitt, M., and Richardson, D. Structure of proteins packing of a-helices and pleated sheets. Proc. Natl. Acad. Set. USA 74, 4130-4134 (1977). Branden, C.-I., Eklund, H., Nordstrom, B., Boiwe, T., Soderlund, G., Zeppeza-uer, E., Ohlsson, I. and Akeson, A. Structure of liver alcohol dehydrogenase at 2.9-A resolution. Proc. Natl. Acad. Sci. USA 70, 2439-2442 (1973). 

Fig. 12 Illustration of the packing of a-helical PELLys-h-PLLeu copolymer chains in the vesicle wall. Reprinted with permission from [52], copyright (2004) Macmillan...

Figure 17 Packing of a helices. Ridges and grooves on the surfaces of a helices lead to three main types of interaction, with angles of 80° (ridges formed by side chains i and j + 3), 60° (ridges formed by side chains i and i+4) or 20° (ridges formed by side chains i and ( + 5) between the main axes of the helices, as shown...

Mixed packings of a helices and P strands. Protein stractures (e.g. alcohol dehydrogenase, triosephosphate isomerase) composed of a heUces and p strands that roughly alternate along the peptide chain (ot/p), can be folded into two classes ... 

The first principle, which governs the amino acids packing in the whole protein, is presented in more detail in Section 2.7. The second principle relies on the observation that quite all the torsion angles and in proteins are located in the allowed region of the Ramachandran diagram. Based on these principles, models for describing the packing of a helices, pleated sheets, and the interactions between helices and pleated sheets have been presented. 

Efimov (1979) from Poustchino s group also emphasized the polarity or hydrophobidty of side chains in the packing of a helices. He developed... 

Packing defects and the existence of cavities inside a protein allow motions in certain parts of the molecule even when localized at the interior. Packing density of the atoms ensures transmission of motion through the protein molecules. The relative rigidity of helix segments, the packing of a helices in sperm whale myoglobin allow the vectorial transmission of motions (Schoenborn, 1971 Richmond and Richards, 1978). 

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