P-Naphthyl acetate

P-Naphthyl acetate. Dissolve 5 0 g. of p-naphthol in 25 ml. of 10 per cent, sodium hydroxide solution in a 250 ml. reagent bottle, add 60 g. of crushed ice, and 5-7 g. (5 -5 ml.) of acetic anhydride. Shake vigorously for 10-15 minutes the p-naphth acetate separates as colourless crystals. Filter with suction, wash with water, drain and dry in the air. Recrystallise from light petroleum (b.p. 60-80°) or from dilute alcohol. The yield of pure product, m.p. 71°, is 6-5 g. 

Decahydro-2-naphthyl acetate. See Decahydro-P-naphthyl acetate Decahydro-p-naphthyl acetate CAS 10519-11-6 EINECS/ELINCS 234-054-3 Synonyms Decahydronaphthol acetate Decahydro-2-naphthyl acetate Empiricai C12H20O2 Properties M.w. 196.29 Uses Fragrance in cosmetics Manuf./Distrib. Advanced Synthesis Tech. http //www.advancedsynthesis.com Decahydro-p-naphthyl formate CAS 10519-12-7 EINECS/ELINCS 234-055-9 Synonyms Decahydro-2-naphthyl methanoate Empiricai C11H18O2 Properties M.w. 182.26 Uses Fragrance in cosmetics Decahydro-p-naphthyl isobutyrate CAS 67874-78-6 EINECS/ELINCS 267-506-3 Synonyms Decahydro-2-naphthyl 2-methylpropanoate Uses Fragrance in cosmetics... 

Naphthyl Acetate. CHgCOOCi H,. Dissolve 1 g. of pure 2-naphtnol in 5 ml. (r8 mols.) of 10% sodium hydroxide solution as before, add 10 g. of crushed ice, and i-i ml. (1-14 g., 1 5 mols.) of acetic anhydride. Shake the mixture vigorously for about 10-15 minutes the 2-naphthyl acetate separates as colourless crystals. Filter at the pump, wash with water, drain, and dry thoroughly. Yield of crude material, 1-4 g. (theoretical). Recrystallise from petroleum (b.p. 60-80 ), from which, on cooling and scratching, the 2-naphthyl acetate separates as colourless crystals, m.p, 71 yield, 10 g. 

Steam distil from a 1 - 5 litre three-necked flask until the odour of nitrobenzene is no longer perceptible in the distillate (6-12 hours). Extract the cold residue with three 100 ml. portions of ether, dry the combined extracts with anhydrous magnesium sulphate, and distil oflF the ether. The residue solidifies and consists of almost pure methyl P-naphthyl ketone, m.p. 52° the yield is 30 g. Upon recrystallisation from glacial acetic acid, the m.p. is raised to 54°. 

The late discovery of acetyl xylan and feruloyl esterases has been partly due to the lack of suitable substrates. Xylans are often isolated by alkaline extraction, in which ester groups are saponified. Treatment of plant materials under mildly acidic conditions, as in steaming or aqueous-phase thermomechanical treatment, leaves most of the ester groups intact. These methods, however, partly hydrolyze xylan to shorter fragments (63,69). Polymeric acetylated xylan can be isolated from delignified materials by dimethyl sulfoxide extraction (70). The choice of substrate is especially important in studies of esterases for deacetylation of xylans. The use of small chromophoric substrates (p-nitrophenyl acetate, a-naphthyl acetate, and methylumbelliferyl acetate) analogously to the assays of disaccharidases may lead to the monitoring of esterases unable to deacetylate xylan (33, 63, 64). 

Naphthyl acetic acid naphthyl acetamide Naphthyl 1 acetonitrile Naphthyl acetic acid 1-Naphthylamine antu, naptalam Neophyl chloride fenbutatin oxide Nicotinic acid diflufenican p-Nitroaniline DCNA (dicloran)... 

To a solution of corresponding imine freshly prepared (1.0 equiv) in dried dichlor omethane at 0 °C, catalyst (13c) (0.1 equiv), (3 naphthol (0.1 equiv), and P naphthyl acrylate (2.0 equiv) were added. The reaction mixture was stirred under argon atmosphere at 0 °C for the required time indicated in the tables. The reaction was stopped by passing the mixture through a short pad of silica gel using ethyle acetate for the elution. Solvents were removed in vacuo and the residue was purified by flash chromatography on silica gel (eluent n Hept/EtOAc = 90/10) to afford the corre spending pure product. 

Ci2H10O, Mr 170.21, 6pi.7kPa 171-173 °C, df 1.171, ng° 1.6752, has been identified in some essential oils. It smells like orange blossom and is a colorless crystalline solid (mp 56 °C). It is usually prepared by Friedel-Crafts acetylation of naphthalene (with acetyl chloride, acetic anhydride, etc.) in the presence of aluminum chloride. In polar solvents (e.g., nitrobenzene), the percentage of the simultaneously formed a isomer is lower. Methyl P-naphthyl ketone is used in eau de cologne, soap perfumes, and detergents. It is a good fixative. 

Schaap, A. P., Handley, R. S., and Giri, B. P., Chemical and enzymatic triggering of 1,2-dioxetanes 1 Aryl esterase-catalyzed chemiluminescence from a naphthyl acetate-substituted dioxetane. Tetrahedron Lett. 28, 935-938 (1987). 

Distil the dry (anhydrous magnesium sulphate) nitrobenzene solution under reduced pressure. Nitrobenzene passes over at 95-100 /16 mm. and the temperature then rises rapidly to 170715 mm. collect the fraction of b.p. 170-180 /16 mm. Transfer whilst still liquid to a porcelain basin it solidifies on cooling. Spread it on a porous tile to absorb the small proportion of liquid a-ketone which is present the resulting yield of crude methyl p-naphthyl ketone, m.p. 40-42°, is 50 g. Two recrystallisations from glacial acetic acid (or from glacial acetic acid - water) give the almost pure p-ketone, m.p. 63 . 

Methyl-1-propanethiol Methyl propionate 3-Methyl-5-propyl-2-cyclohexen-1 -one Methyl propyl ketone 2-Methylpyrazine flavoring agent, synthetic food Methyl salicylate Methyl sorbate 5-Methyl-2-thiophenecarboxyaldehyde 3-Methylthiopropionaldehyde 2-Methyl-3-tolylpropionaldehyde, mixed o-, m-, p-Methyl 9-undecenoate Methyl 2-undecynoate Methyl valerate MSG Musk ambrette Myrcene Myristaldehyde Myristyl alcohol Myrtenol 2-Naphthalenethiol P-Naphthyl ethyl ether P-Naphthyl isobutyl ether d-Neomenthol Nerol Neryl acetate Neryl butyrate Neryl formate Neryl isobutyrate Neryl isovalerate Neryl propionate... 

Methyl propionate 3-Methyl-5-propyl-2-cyclohexen-1-one Methyl propyl ketone Methyl tiglate Methyl p-toluate Methylundecanal dimethyl acetal Methyl 9-undecenoate Methyl 10-undecenoate Methyl valerate Methyl vanillate Musk ketone Musktibetene Myrcene Myrcenol Myrcenyl acetate Myristaldehyde Myrrh gum Myrtenol Myrtenyl acetate Myrtenyl formate Myrtle (Myrtus communis) extract Myrtle (Myrtus communis) oii P-Naphthyi isobutyl ether P-Naphthyl methyl ether Neral Nerol Neryl acetate Neryl butyrate Neryl formate Neryl isobutyrate Neryi isovaierate Neryi propionate Nona-2,4-dienai trans,trans-2,4-Nonadienal 2,6-Nonadien-1-ol... 

Amyl isovalerate P-Naphthyl methyl ether 2-(3-Phenylpropyl) tetrahydrofuran Snakeroot (Asarum canadense) oil tobacco ingredient Bornyl acetate... 

M. expansa was cytosolic and conjugated CDNB but not bromobenzene or chlorobenzene (Douch and Buchanan 1978). Similarly, glutathione-S-transferase activity in H. contortus was observed only with CDNB as substrate and not with DCNB or l,2-epoxy-3-(p-nitrophenoxy)propane (Kawalek et al. 1984). Neither M. expansa not A. suum produced glucuronides with 4-nitrophenol, 2-aminophenol or 4-methylumbelliferone (Douch and Blair 1975), or possessed measurable DDT-dehydrochlorinase activity (Douch and Buchanan 1978). Various specific (cholinesterase) and non-specific esterases have been detected in trematodes, e.g. using a-naphthyl acetate as substrate, in A laria marcianae (Dickinson and Johnson 1978) and Schistosoma mansoni and Schistosoma haematobium (Coles 1970). 

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