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P-glycoprotein multidrug transporter

Romsicki, Y., Sharom, F. J., Phospholipid flippase activity of the reconstituted P-glycoprotein multidrug transporter, Biochemistry 2001, 40, 6937-6947. [Pg.488]

The bihary and renal excretion of some drugs (e.g., anthracyclines, vinca alkaloids, dactinomycin, etopo-side) by the P-glycoprotein multidrug transporter can be inhibited by other drugs that are also transported by P-glycoprotein. [Pg.635]

Fardel O, Lecureur V, Guillouzo A. The P-glycoprotein multidrug transporter. Gen Pharmacol 1996 27(8) 1283-1291. [Pg.409]

Romsicki Y, Sharom FJ. The membrane lipid environment modulates drug interactions with the P-glycoprotein multidrug transporter. Biochemistry 1999 38 (21) 6887-6896. [Pg.419]

Romsicki Y, Sharom FJ (1999) The mebrane lipid environment modulates drug interactions with P-glycoprotein multidrug transporter. Biochemistry 38 6887-6896 Schwab D, Fischer H, Tabatabaei A, Poli S, Huwyler J (2003) Comparison of in vitro P-glycoprotein screening assays recommendations for their use in drug discovery. J Med Chem 46(9) 1716—1725... [Pg.453]

Eckford PD, Sharom FJ (2005) The reconstituted P-glycoprotein multidrug transporter is a flip-pase for glucosylceramide and other simple glycosphingolipids. Biochem J 389 517-526... [Pg.1689]

Liu, R., Siemiarczuk, A., and Sharom, F.J. (2000) Intrinsic fluorescence of the P-glycoprotein multidrug transporter sensitivity of tryptophan residues to binding of drugs and nucleotides. Biochemistry, 39 (48), 14927-14938,... [Pg.43]

P-glycoprotein multidrug transporter (P-gp) on drug absorption has been studied extensively. Since P-gp is located on the epithelium of intestinal cells, it can act as a countertransport pump that transports its substrates back into the intestinal lumen as they begin to be absorbed across the intestinal wall. [Pg.643]

Yamazaki, M., Li, B., Louie, S.W., Pudvah, N.T., Stocco, R., Wong, W., Abramovitz, M., Demartis, A., Laufer, R., Hochman, J.H., Prueksaritanont, T. and Lin, J.H. (2005) Effects of fibrates on human organic anion-transporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transport. Xenobiotica, 35, 737-753. [Pg.361]

Sharma V, Piwnica-Worms D (2005) Monitoring Multidrug Resistance P-Glycoprotein Drug Transport Activity with Single-Photon-Emission Computed Tomography and Positron Emission Tomography Radiopharmaceuticals. 252 155-178 Shinkai S, see Ishi-i T (2005) 258 119-160... [Pg.205]

Teft WA et al (2011) Endoxifen, the active metabolite of tamoxifen, is a substrate of the efflux transporter P-glycoprotein (multidrug resistance 1). Drug Metab Dispos 39 558-562... [Pg.248]

Yamazaki M, Li B, Louie SW, et al. Effects of fibrates on human organic aniontransporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transport. Xenobiotica 2005 35 737-753. [Pg.85]

Juranka PF, Zastawny RL, Ling V. P-glycoprotein multidrug-resistance and a superfamily of membrane-associated transport proteins. FASEB J 1989 3(14) 2583-2592. [Pg.409]

Monitoring Multidrug Resistance P-Glycoprotein Drug Transport Activity with Single-Photon Emission Computed Tomography and Positron Emission Tomography Radiopharmaceuticals... [Pg.155]

Monitoring Multidrug Resistance P-Glycoprotein Drug Transport Activity... [Pg.157]


See other pages where P-glycoprotein multidrug transporter is mentioned: [Pg.574]    [Pg.574]    [Pg.265]    [Pg.226]    [Pg.42]    [Pg.308]    [Pg.321]    [Pg.234]    [Pg.284]    [Pg.198]    [Pg.308]    [Pg.215]    [Pg.127]    [Pg.195]    [Pg.242]    [Pg.258]    [Pg.237]    [Pg.61]   
See also in sourсe #XX -- [ Pg.25 , Pg.253 ]




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Multidrug transporters

P-glycoprotein

P-glycoprotein transport

P-glycoprotein transporter

P-transport

Transport glycoprotein

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