Oximes compounds

For oximes, the word oxime is placed after the name of the aldehyde or ketone. If the carbonyl group is not the principal group, use the prefix hydroxyimino-. Compounds with the group Z = N—OR are named by a prefix alkyloxyimino- as oxime O-ethers or as O-substituted oximes. Compounds with the group r C=N(0)R are named by adding A-oxide after the name of the alkylideneaminc compound. For amine oxides, add the word oxide after the name of the base, with locants. For example, C5H5N—O is named pyridine A-oxide or pyridine 1-oxide. 

Oxime carbamates are not directly amenable to gas chromatography (GC) because of their high thermal instability, which often leads to their breakdown at the injection port or in the column during analysis. Analysis of oxime carbamates by GC with sulfur detection or flame photometric detection involves oxidation of the intact insecticides or alkaline hydrolysis to form the more volatile but stable oxime compound. Enzymatic techniques have been reported for the analysis of these compounds. Enzyme-linked immunosorbent assay (ELISA) has been used to determine aldicarb and its sulfone and sulfoxide metabolites and methomyl in water, soil, and sediment samples. 

Rather than the expected [3 + 2] cycloaddition, a novel ene-like cycloisomerization occurs on deprotonation of allyltrimethylsilyl-oxime compounds, when the j3-sp2 carbon atom of the allyltrimethylsilyl moiety is tethered to the oxime unit. The resulting nitrile oxide group serves as an enophile, and the final cyclized product still has two functional groups suitable for further manipulations. Thus, ene-like cycloisomerization of allyltrimethylsilyl-oxime 375 with NaOCl in CH2CI2 gives 82% of cyclized product 376 (423). See also Reference 424. 

In view of the dual bonding modes of NO, migratory insertion (107) is not the only transformation of this type that can be envisioned. In (108), the nitrosyl is coordinated as NO", and the migration of the R group to form a coordinated nitroso or oxime compound can be viewed, at least heuristically, as a 1,2-shift of R+. 

Iso-nitroso and Oxime Compounds.—This iso-nitroso derivative of the mono-ketone (methyl ethyl ketone) is also an oxime of the di-ketone (di-acetyl) as may be shown by the following relationships. 

Aldehyde and Ketone Reactions.—(i) The formation of addition prodmts with hydrogen cyanide, H—CN. (2) The formation of oxime compounds with hydroxyl amine, H2—NOH. (3) The formation of hydrazone compounds with a benzene compound known as phenyl hydrazine, H2N—NH—CeHs. 

Oximes - Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes those from ketones may be called ketoximes. [5]... 

CAN-mediated nitration provides a convenient route for the introduction of a nitro group into a variety of substrates. Alkenes on treatment with an excess of sodium nitrite and CAN in chloroform under sonication afford nitroalkenes. When acetonitrile is used as the solvent, nitroacetamidation occurs in a Ritter-type fashion. However, the attempted nitroacetamidation of cyclo-pentene-1 -carboxaldehyde under similar conditions resulted in the formation of an unexpected dinitro-oxime compound. A one-pot synthesis of 3-acetyl- or 3-benzoylisoxazole derivatives by reaction of alkenes (or alkynes) with CAN in acetone or acetophenone has been reported. The proposed mechanism involves a-nitration of the solvent acetone, oxidation to generate the nitrile oxide, and subsequent 1,3-dipolar cycloaddition with alkenes or alkynes. The nitration of aromatic compounds such as carbozole, naphthalene, and coumarins by CAN has also been investigated. As an example, coumarin on treatment with 1 equiv of CAN in acetic acid gives 6-nitrocoumarin in 92% yield. ... 

For B12 model compounds, several studies concerning anaerobic photolysis of alkylcobaloximes with nitrogen donor bases have been made. Recently, a work on photolysis cobaloximes and imino/oxime compounds controlled by steric hindrance imposed by the Lewis base has been investigated. ... 

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