Oxidative LDL theory and antioxidant activity of flavonoids in plasma

4 Oxidative LDL theory and antioxidant activity of flavonoids in plasma 

Natume et al., 2003). Plasma obtained 1 h after ingestion of 1 g EC was used for the measurement 

Taken together, it can be concluded that the contribution of dietary flavonoids to plasma antioxidant defense is small or limited only to special cases such as an excessively high dose of flavonoid-rich supplements. The idea that dietary flavonoids are helpful in LDL protection from oxidative modification should be reconsidered, and insight into a more specific target site is necessary to understand the mechanism of action of dietary flavonoids as antiatherosderotic food factors. 

---