Ox Bile Extract

Ox Bile Extract occurs as a yellow-green powder. It contains ox bile acids, chiefly glycocholic and taurocholic, as sodium salts, equivalent to not less than 45.0% cholic acid, C24H40O5. It is the purified portion of the bile of an ox, obtained by evaporating the alcohol extract of concentrated bile. It is soluble in water and in alcohol. 

Sodium salt, CMHj,NaOj, sodium cholale. Crystals. Soly in water at t5° > 568.9 g/l. Caution The names "sodium cholate and sodium choleate" are sometimes used for mixtures of bile sails. The term "sodium choleate" is to be preferred for bile salts, see Ox Bile Extract. 

USE Sodium salt is a lipase accelerator. See also Ox Bile Extract. 

Cholic acid, deoxy-. See Desoxycholic acid Cholic acid, monosodium salt Cholic acid sodium salt. See Ox bile extract Choline alfoscerate. See Glycerophosphocholine Choline bicarbonate CAS 78-73-9 EINECS/ELINCS 201-137-0 Synonyms Hydrogen carbonate 2-Hydroxyethyltrimethyl ammonium Classification Nonaromatic amine Empirical C6H15NO4 Formula (CH3)3NCH2CH20H HCO3 Properties Colorless liq. m.w. 165.19 dens. 

Extract GLM No. 1. See Mammary extract Extract of Ox Bile NFXI. See,Ox bile extract Extract of Whole Grapefruit. See Grapefruit (Citrus grandis) oil... 

H,3H,5H-Oxazolo [3,4-c] oxazole-7a(7H)-methanol. See Hydroxymethyl dioxoazabicyclooctane Oxazolo (3,4-c) oxazole, poly (oxymethylene) deriv.. See Polymethoxy bicyclic oxazolidine Oxazolo [3,4-c] oxazol-7a-yl-methanol. See Hydroxymethyl dioxoazabicyclooctane Ox bile extract... 

Purified gum spirits. See Turpentine Purified oxgall. See Ox bile extract Purified water. See Water 1H-Purin-6-amine. See Adenine 7H-Purine-7-acetic acid, 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-, dihydroxymethylsilyl ester. See Methylsilanol carboxymethyl theophylline... 

Sodium cholate Sodium cholic acid. See Ox bile extract... 

Calf skin extract Tapioca starch nutritive pharmaceutical additive Ox bile extract nutritive polymer, food Maltodextrin... 

Nonoxynol-6 Nonoxynol-10 Nonoxynol-40 Nonoxynol-50 Octoxynol-8 Octoxynol-9 Octoxynol-13 Ox bile extract PEG-4 castor oil PEG-4 dilaurate PEG-6 dilaurate PEG-32 dilaurate PEG-75 dilaurate PEG-150 dilaurate PEG-4 dioleate PEG-6 dioleate PEG-20 dioleate PEG-32 dioleate PEG-75 dioleate PEG-150 dioleate PEG-6 distearate PEG-20 distearate PEG-32 distearate PEG-75 distearate PEG-150 distearate... 

Orange (Citrus aurantium dulcis) oil 8008-63-7 Ox bile extract 8008-74-0 Cropure Sesame EmCon SES Hy-SES Lipovol SES Phytol SES Sesame Oil USP/NF 16 Sesame (Sesamum indicum) oil Super Refined Sesame NF Tri-OI SES Uniderm SSME Vitinc Sesame Oil NF 8008-79-5 EmCon Spearmint Eromenth ... 

Ox bile extract C24H40O4 Desoxycholic acid C24H40O5 Cholic acid C24H41NO2... 

One such synthesis began with desoxycholic acid (from ox bile), which was laboriously converted to cortisone in 32 steps, many of which were required to transpose the oxygen function from the 12 to the 11 position, to introduce the 17 a-hydroxyl and to construct the a,P-keto arrangement in ring A. Over a 3-year period (1946-1949) some 1,200 pounds of the bile acid laboriously yielded less than 1 kg of cortisone. Workers at the Mayo Clinic (Hensch et al., 1949) reported on their dramatic success in controlling rheumatoid arthritis pain with cortisone. This gave the impetus to find a better way to provide cortisone than by the 32-step synthesis from desoxycholic acid or the laborious extraction from ox adrenals. 

Medici and co-workers [22] isolated and classified several microorganisms from 50 environmental samples withdrawn from ICE industry [23], which extracts and purifies bile acids from raw materials (ox and pig bile). These microorganisms (mostly bacteria) have been screened in oxidation reactions of cholic 1, chenodeoxycholic 34, deoxychdlic 40, and hyocholic 31 acids. The most significant results are summarized in Table 7. 

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