Outer motor protein

Two other projections adorn each peripheral microtubule they are called the outer arm and the inner arm. Biochemical analysis has shown that these projections contain a protein called dynein. Dynein is a member of a class of proteins called motor proteins, which function as tiny motors in the cell, powering mechanical motion. ... 

Nagy I, Bodmer M, Schmid S, Bodmer D. 2005. Promyelocy-tic leukemia zinc finger protein localizes to the cochlear outer hair cells and interacts with prestin, the outer hair cell motor protein. Hear Res 204 216-222. 

Navaratnam D, Bai JP, Samaranayake H, Santos-Sacchi J. 2005. N-terminal mediated homo-multimerization of prestin, the outer hair cell motor protein. Biophys J. 

Santos-Sacchi J, Shen W, Zheng J, Dallos P. 2001. Effects of membrane potential and tension on prestin, the outer hair cell lateral membrane motor protein. 1 Physiol 531 661-666. 

Zheng J, Shen W, He DZ, Long KB, Madison LD, et al. 2000. Prestin is the motor protein of cochlear outer hair ceUs. Nature 405 149-155. 

Movement of motor protein toward the (-I-) end or (—) end of microtubules, t Outer-arm dyneins have three heavy chains, and inner-arm d3uieins have two heavy chains. 

SCL26A5 (PRES) Prestin Outer hair oells Motor protein 7q21-31 Autosomal recessive deafness DFNB61 604943... 

Proteins act as enzymes, hormones, and antibodies. They maintain fluid balance and acid and base balance. They also transport substances such as oxygen, vitamins, and minerals to target cells throughout the body. Structural proteins, such as collagen and keratin, are responsible for the formation of bones, teeth, hair, and the outer layer of skin, and they help maintain the structure of blood vessels and other tissnes. In contrast, motor proteins use energy and convert it into some form of mechanical work (e.g., dividing cells and contracting muscle). 

For externalization of the flagella, a different system is used-the type III secretory system. The flagellar motor proteins are part of this, and a specialized protein is also present in the outer membrane that allows extrusion of the flagellar protein in proper orientation through both membranes. That type IV secretion exists in the organism, with direct injection of bacterial protein into host cells, has also been suggested. 

Santos-Sacchi, J. Zhao, H. B. Excitation of fluorescent dyes inactivates the outer hair cell integral membrane motor protein prestin and betrays its lateral mobility. 

Fig-i Mitochondrial protein import machinery as defined in S. cerevisiae. TOM translo-case of the outer mitochondrial membrane SAM sorting and assembly machinery TIM translocase of the inner mitochondrial membrane MIA mitochondrial IMS import and assembly machine PAM presequence translocase associated motor IMP inner membrane protease MPP mitochondrial processing peptidase. The numbers on the individual Tom, Sam, Tim or Pam components represent their approximate molecular masses in kDa. See text for mechanistic details. Adopted from Dolezal et al. 2006... 

Fibrous proteins represent a substantial subset of the human proteome. They include the filamentous structures found in animal hair that act as a protective and thermoregulatory outer material. They are responsible for specifying much of an animal s skeleton, and connective tissues such as tendon, skin, bone, cornea and cartilage all play an important role in this regard. Fibrous proteins are frequently crucial in locomotion and are epitomised by the muscle proteins myosin and tropomyosin and by elastic structures like titin. Yet again the fibrous proteins include filamentous assemblies, such as actin filaments and microtubules, where these provide supporting structures and tracks for the action of a variety of molecular motors. 

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