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Other Chemokines and their Receptors

Matsukawa A, Lukacs NW, Hogaboam CM, Chensue SW, Kunkel SL 111. Chemokines and other mediators, 8. Chemokines and their receptors in cell-mediated immune responses in the lung. Microsc Res Tech 2001 53 298-306. [Pg.198]

Antagonism of chemokines and their receptors represents an attractive and potentially effective means of modulating inflammatory responses, and it may prove to be a useful therapeutic strategy for atherosclerosis and many other inflammatory diseases. Successful therapeutic intervention is based on selective disease modification with minimal impact on the normal physiological processes so as to limit the side effects of treatment. Due to the complexity of the chemokine hemokine receptor system, the inherent redundancy... [Pg.235]


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