Oropharyngeal cavity

A mouthpiece. The mouthpiece may be used to control the direction of the aerosol cloud in the mouth and throat, in order to reduce drug deposition in the oropharyngeal cavities. De Boer et al. [55] use a so-called sheath flow to reduce mouth deposition. 

The symptoms of oropharyngeal anthrax include swelling of the neck, and lesions in the oral cavity (similar to cutaneous lesions), sometimes on the tonsils. Other symptoms include fever, swollen lymph nodes, and inability to swallow. Shock and toxemia can characterize both forms of the disease. The fatality rate for gastrointestinal anthrax ranges from 25 to 60%.3... 

Oropharyngeal symptoms Swelling of neck Lesion in oral cavity... 

The patient s inspiratory flow rate also affects impaction of aerosol particles in the oral cavity. Data from a study by Anderson et al. show the effect of increasing inspiratory flow rate on oropharyngeal deposition of an aerosol with 3.0-pm MM AD (6). In that study, the authors increased flow rate from 0.4 to 1.2 L/s in a group of normal subjects. The aerosol was generated by nebulizer, so there was no additional effect of pressurized propellant. As inspiratory flow rate increased, average deposition in the oral cavity increased from 20 to 38%. 

---