Organization development through

Fujimi TJ, Hatayama M, Amga J. Xenopus Zic3 controls notochord and organizer development through suppression of the Wnt/p-calenin signaling pathway. Dev Biol. 2012 36 220-31. 

Large numbers of activated macrophages surround the solid caseous (cheese-like) TB foci (the necrotic area) as a part of cell-mediated immunity. Delayed-type hypersensitivity also develops through activation and multiplication of T lymphocytes. Macrophages form granulomas to contain the organisms. 

Membrane-Interaction (MI)-QSAR approach developed by Iyer et al. was used to develop predictive models of some organic compounds through BBB, and to simulate the interaction of a solute with the phospholipide-rich regions of cellular membranes surrounded by a layer of water. Molecular dynamics simulations were used to determine the explicit interaction of each test compound with the DMPC-water model (a model of dimyristoylphosphatidylcholine membrane monolayer, constructed using the software Material Studio according to the work done by van der Ploeg and Berendsen). Six MI-QSAR equations were constructed (Eqs. 74-79) ... 

Stem cells are present in the earliest stage of embryonic development the blastocyst. Embryonic stem cells are pluripotent, meaning they are capable of generating any terminally differentiated cell in the human body that is derived from any one of the three embryonic germ layers ectoderm, mesoderm, or endoderm [8]. All the body s organs arise through a series of divisions and differentiations from the original embryonic stem cells that form the blastocyst [3]. 

Continued exposure to a teratogen may produce cumulative effects or may affect several organs going through varying stages of development. Chronic consumption of high... 

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