Organic reactions—continued general types

Three methodologies are compared the classical solution method, the Merrifield approach and an automated (the "mediatcontinuous monitoring. The utilization of PRs as general acyl transfer reagents is also elaborated. ITie described approaches are not limited to peptide synthesis, but may be applicable to a wide range of organic reaction types. 

In the fourth and final chapter, Howard Haubenstock discusses asymmetric reduction of organic molecules. Within this general topic of wide and continuing interest, Haubenstock s chapter deals with chiral derivatives of lithium aluminum hydride, their preparation from suitable amino or hydroxy compounds, and their use in reducing carbonyl groups. Related reactions of the Meerwein-Ponndorf-Verley type or involving tri-alkylaluminum reagents are also presented. 

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