Organic-Inorganic Hybrid Vesicle Cerasome

16 Layered magnesium organophyl osi icates. Adapted from [76], Y. Fukushima and M. Tani, Bull, chem Soc Ian 1996 69, 3667. 

All of the above-mentioned examples describe organosiloxane hybrid sheet-like structures. However, cell-mimicry requires spherical structures that can form an inner space as a container. Liposomes and lipid bilayer vesicles are known as models of a spherical cell membrane, which is a direct mimic of a unicellular membrane. However, the limited mechanical stability of conventional lipid vesicles is often disadvantageous for some kinds of practical application. 

Formation of cerasome assemblies is not limited to unintentional aggregation as described above. Subjecting the cerasome structure to LbL techniques could result in 

Adsorption Cycle Fig. 2.23 QCM responses on LbL assemblies (a) LbL assembly between dihexadecyl phosphate vesicle and PDDA (b) LbL assembly between anionic cerasome (larger step) and PDDA (smaller step) (c) LbL assembly between anionic cerasome (larger step) and cationic 

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Figure 2.8 (a) Illustration of an organic—inorganic hybrid vesicle cerasome and its TEM image, (b) LbL... 

K. Katagiri, K. Ariga, J. Kikuchi, Preparation of Organic-Inorganic Hybrid Vesicle Cerasome Derived from Artificial Lipid with Alkoxysilyl Head , Chem. Lett, 661 (1999)... 

Figure 11 shows an example of EELS mapping of an organic-inorganic hybrid vesicle, cerasome, coated with the Ni-nanometal layer. The specimen was prepared by... 

Figure 4.29. Organic-inorganic hybrid vesicle known as a cerasome ...

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