Cerasomes

Fig. 2.19 Preparation of cerasome from alkoxysilane-bearing amphiphiles. Adapted from [29], K. Ariga, Chem. Rec. 2004, 3,297.

Formation of cerasome assemblies is not limited to unintentional aggregation as described above. Subjecting the cerasome structure to LbL techniques could result in... 

Fig. 2.22 LbL assembly of cerasome (A) LbL assembly between anionic cerasome and cationic polyelectrolyte (B) LbL assembly between anionic cerasome and cationic cerasome.

Adsorption Cycle Fig. 2.23 QCM responses on LbL assemblies (a) LbL assembly between dihexadecyl phosphate vesicle and PDDA (b) LbL assembly between anionic cerasome (larger step) and PDDA (smaller step) (c) LbL assembly between anionic cerasome (larger step) and cationic... 

Katagiri K, Hamasaki R, Ariga K et al (2002) Layer-by-layer self-assembling of liposomal nanohybrid cerasome on substrates. Langmuir 18 6709-6711... 

Figure 2.8 (a) Illustration of an organic—inorganic hybrid vesicle cerasome and its TEM image, (b) LbL... 

Figure 4.29. Organic-inorganic hybrid vesicle known as a cerasome ...

This structure is called a cerasome because it has both a ceramic-like surface and a liposome-Uke cell structure. The cerasome is mechanically stable and can be further assembled into a multivesicle form without causing the vesicular structure to collapse. 

K. Katagiri, K. Ariga, J. Kikuchi, Preparation of Organic-Inorganic Hybrid Vesicle Cerasome Derived from Artificial Lipid with Alkoxysilyl Head , Chem. Lett, 661 (1999)... 

Figure 11 shows an example of EELS mapping of an organic-inorganic hybrid vesicle, cerasome, coated with the Ni-nanometal layer. The specimen was prepared by... 

Figure 11 TEM image of Ni-coated cerasome (a) and the corresponding EELS mapping for C (b), Si (c), and Ni (d). (Reproduced with permission from Ref. 26. Ceramic Society of Japan, 2008.)...

FIGURE 6. Silica-based hybrid vesicle, cerasome. 

This technique can be applied to LbL assembly of cerasomes because, like silicas, they possess surface charge. Initial attempts entailed LbL assembly between cationic polyelectrolyte and anionic cerasomes with monitoring by using QCM, and where reasonable frequency shifts in the QCM response were observed. Morphology of the assembled structure was also confirmed... 

FIGURE 11. LbL assembly between cationic and anionic cerasomes. 

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