Order penetration point

Order penetration point The point in a product s flow when an item is earmarked for a particular customer. Downstream processes are driven by customer orders upstream processes are driven by forecasts and plans. However, the plans themselves can reflect actual customer orders in a demand-driven supply chain. (Adapted from APICS Dictionary, lOtb edition )... 

Olhager, J. (2003). Strategic positioning of the order penetration point International Journal of Production Economics, 85(3), 319-329. 

Using the principle of order decoupling (order penetration point) is one way of responding to demand volatility in real time. For example, in a build-to-order (BTO) environment the supplier builds the product from scratch (component... 

In many cases companies have an inadequate visibility of real demand. By real demand we mean the demand in the final marketplace, not the derived demand that is filtered upstream through any intermediary organisations that may lie between the company and the final user. The challenge is to find a way to receive earlier warning of the customers requirements. What we frequently find is that, firstly, the demand penetration point is too far down the pipeline and, secondly, real demand is hidden from view and all we tend to see are orders. Both these points need further explanation we will deal with the concept of the demand penetration point first. 

Where D-times are a measure of the importance of speed as a competitive factor, while P-times measure the ability to deliver. The integration of the two measures the point at which the customer order penetrates the supply chain. In Chapter 5 and Chapter 6, p. 176, we develop this issue in terms of the customer order decoupling point. 

This study has been launched in order to provide quantified data about the compared performances of liquid penetrant product family and, finally, to introduce an acceptance criteria on performance of liquid penetrant range of products in RCC-M code which had no requirement on that point. 

The three prototype mixed p agonist/S antagonists described in this chapter have excellent potential as analgesics with low propensity to produce tolerance and dependence. The pseudotetrapeptide DIPP-NH2[ ] has already been shown to produce a potent analgesic effect, less tolerance than morphine, and no physical dependence upon chronic administration. In preliminary experiments, the tetrapeptides DIPP-NH2 and DIPP-NH2[T] were shown to cross the BBB to some extent, but further structural modifications need to be performed in order to improve the BBB penetration of these compounds. The Tyr-Tic dipeptide derivatives can also be expected to penetrate into the central nervous system because they are relatively small, lipophilic molecules. In this context, it is of interest to point out that the structurally related dipeptide H-Dmt-D-Ala-NH-(CH2)3-Ph (SC-39566), a plain p-opioid agonist, produced antinociception in the rat by subcutaneous and oral administration [72], As indicated by the results of the NMR and molecular mechanics studies, the conformation of the cyclic p-casomorphin analogue H-Tyr-c[-D-Orn-2-Nal-D-Pro-Gly-] is stabilized by intramolecular hydrogen bonds. There-... 

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