Oral drug delivery technology

Even if there have been advances in oral drug delivery technologies during the last 50 years, many highly sophisticated drug delivery systems have failed and have... 

Extended-Release Oral Drug Delivery Technologies Monolithic Matrix Systems... 

Choonara, B.F., Choonara, Y.E., Kumar, P., Bijukumar, D., du Toit, L.C., Pillay, V., 2014. A review of advanced oral drug delivery technologies facihtating the protection and absorption of protein and peptide molecules. Biotechnology Advances 32, 1269-1282. 

Sachan NK (2009) Biopharmaceutical classification system a strategic tool for oral drug delivery technology. Asian J Pharm 3 76—81... 

S.B. Tiwari, and A.R. Siahboomi, Extended-release oral drug delivery technologies Monolithic matrix systems, in KK. Jain, ed.. Drug Delivery Systems, Humana Press, Totowa, NJ, 217-243, 2004. 

Wilson CG, O Mahony B, Lindsay B. Physiological factors affecting oral drug delivery. In Swarbrick J, ed. Encyclopaedia of Pharmaceutical Technology. New York Marcel Dekker, 2002 2214-2222. 

Despite tremendous innovations in the field of drug delivery technology, oral intake remains the preferred route of drug administration, for reasons of patient convenience and therapy compliance. Compounds intended for oral administration must have adequate biopharmaceutical properties in order to achieve therapeutic concentrations at the targeted site of action. 

In recent years, drug delivery technologies have grown extensively that go beyond conventional oral dosage forms. For example, intravenous, transdermal, and implant technologies are widely used for sustained drug delivery over increased periods of time. The type of drug, its characteristics, and the intended indication determine the mode of delivery. 

Table 2 Examples of Polymer-Based Technologies Used for Oral Drug Delivery... 

P. Kearney. The Zydis oral fast-dissolving dosage form, in Michael J. Rathbone, Jonathan Hadgraft, and Machael S. Roberts (eds.), Drugs and the Pharmaceutical Sciences, Vol. 126 Modified-Release Drug Delivery Technology. New York Marcel Dekker, 2003, pp. 191-201. 

Brayden, D.J. and O Mahony, D.J. (1998) Novel oral drug delivery gateways for biotechnology products polypeptides and vaccines. Pharmaceutical Science and Technology Today, 1 291-299. 

Describe the current technologies in oral drug delivery,... 

Gebhart, F. (1991). CTA uses protemoid technology to break into oral drug delivery market. Genetic Engineering News May, 6 7. 

Sastry SV, Nyshadham JR, and Fix JA. Recent technological advances in oral drug delivery—a review. PSTT. 2000 3(4) 138-145. 

Brown, D. Orally disintegrating tablets—taste over speed. Drug Delivery Technology 2003, 3 (6), 58-61. 

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