Oral cavity epithelial lining

Visual inspection of the oral cavities (mouth) of the dogs did not reveal any evidence of lesions, redness or changes in the mucosal linings attributable to Ora-lin use. Epithelial scrapings from each site, for evaluation of the oral cavity, did not reveal any evidence supportive of toxic injury - that is, there was no evidence of epithelial structural changes or changes in cell structure or mucosal linings. 

The gastrointestinal tract includes the oral cavity, the stomach, the small intestines, the large intestine, and the rectum. The entire system is lined with epithelial cells, which typically have tight junctions between them which are rel-... 

Various transport processes used by low molar mass drugs to cross the epithelial barrier lining oral, buccal, nasal, vaginal, and rectal cavities include passive diffusion, carrier-mediated transfer systems, and selective and nonselective endocytosis. Additionally, polar materials can also diffuse through the tight junctions of epithelial cells (the paraceUular route). Evidence also exists that suggests that macromolecules (particulate... 

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