System Optimisation

Micro-Scaled Lead Generation and Optimisation Systems... 

Fig. 1. Schematic diagram of lead discovery and optimisation system...

NEW OPTIMISED SYSTEM FOR THE LEAD FREE CROSSLINKING OF EPICHLOROHYDRIN (ECO) ELASTOMER... 

In order to slow down the overall reaction we added acetic anhydride as a diluent, thereby giving the zeolite a better chance to exert an influence over the reaction. Indeed, this led to a slower reaction and zeolite HP then exerted a greater influence over both the rate and selectivity. The yield after 2 h at -10 °C in the absence of the zeolite was only 16 % and the 2 3 ratio was the usual 2 1, but with the zeolite present the yield increased to 99 % and the ratio to 17 1. p-Nitrotoluene could also be nitrated with the optimised system used for o-nitrotoluene, but the reaction was much slower. Therefore, for direct dinitration of toluene it would be necessary to minimise the amount of the diluent used. 

US Patent (2000) Log cutting optimisation system (Weyerhaeuser Inc.). No. 6026689 USDA (1965) Western wood density survey report No. 1. USDA, Forest Service, Forest Products Laboratory, Research Paper FPL 27... 

Ideally, for an optimised system architecture, the appropriate HAV or S/W DALs should be flown down from the Level 4 design team. 

Richei, A., Hauptmanns, U, Unger, H. 2001. The human error rate assessment and optimising system HEROS- a new procedure for evaluating and optimizing the man-machine interface in PSA. Reliability Engineering and System Safety. 72 153 164. 

Racemisation via Sn2 displacement has been used for the DKR of a a-bromoester by enzymatic hydrolysis the product, a a-bromoacid, was less reactive in the Sn2 process. Investigations of the bromide source and the lipase employed led to an optimised system where an immobilised phosphonium bromide was used, together with cross-linked enzyme crystals from Candida rugosa lipase (CLEC-CRL), to afford the corresponding a-bromocarboxylic acid (Scheme 3.37). This procedure could be extended to a-chloroesters. 

NATS have considerable experience. Although we could adjust more parameters and adjust parameters over a greater range, the strategy adopted here provides an assurance that the optimised system is still operating within the usual parameter ranges. 

Perkin Elmer supply a system 2000 TGA-IR interface. This is a single supplier fully optimised system with a powerful range of advanced graphics and post-run processing software including the ability to produce stack plots showing small changes and trends... 

Finally, it is worth noting that the development of adaptronic components to be used for the most diverse machine tools and manufacturing plants is a multidisciplinary task requiring the collaboration of production, civil, machine and control engineers. A multidisciplinary approach of this task is crucial for the successful implementation of optimised systems with structurally integrated actuators and sensors and adaptive control algorithms in machine tool applications. 

Fig. 2.19 CARBOFLEX - continuous carbon control and optimising system on a pusher furnace.

Kobbaty K.A.H. and I Jeon. 2001. The development of a Hybrid Intelligent Maintenance Optimisation System (HIMOS) . Journal of the Operational Research Sod-ety (2001) 52, 762-778. 2001 Operational Research Sodety Ltd. All rights reserved. 0160-5682/01. 

The orthophosphate dosing scenario A with M = 0.02 and = 30 is typical of many optimised systems in the UK and should be achievable with a relatively low orthophosphate dose. It is predicted that LCR compliance would be achieved, based on the first litre drawn after stagnation, but not if compliance was based on further sequential samples. This is also the case with B when M= 0.015 and E = 22.5. To achieve LCR compliance based on sequential sampUng would require M= 0.01 and =15 (scenario C), likely to be at the extreme range of orthophosphate s abihty to suppress lead solvency. Laboratory plumbosolvency testing will be necessary to confirm the orthophosphate dosing response of the water in City A (i.e. the doses required for scenarios A, B and C), and would help to confirm these comphance predictions (which would be subject to operational feasibility). 

---