Optimal Side-Stream Location and Flowrate

ACETIC ACID-WATER (ISOBUTYL ACETATE AS THE ENTRAINER) 

2 Closed-Loop Dynamic Simulations with Load Disturbances 

The temperature at Stage 9 is selected as the control point since it shows the least deviation from base-case conditions. 

Since there are two other potential manipulated variables (reboiler heat duty and side-draw flowrate) for product quality control, a more complicated two-point or even 

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