Optic nerve transection

Measurement of amino acid levels in the vitreous humor of rats after chronic intraocular pressure elevation or optic nerve transection. Glaucoma 11, 396—405. 

Butt, A. M. and Colquhoun, K., Glial cells in the transected optic nerves of immature rats. I. An analysis of individual cells by intracellular dye-injection, J. Neurocytol., 6, 365, 1996. 

Schnitzer, J. and Scherer, J., Microglia cell responses in the rabbit retina following transection of the optic nerve, J. Comp. Neurol., 302, 779, 1990. 

Sievers, J., Hausmann, B., Unsicker, K. and Berry, M. (1987) Fibroblast growth factors promote the survival of adult rat retinal ganglion cells after transection of the optic nerve. Neurosci. Lett. 76 157-162. 

After postcommissural fornix transection (Lips et al., 1995) and after optic nerve lesion (Ajemian et al., 1994) in adult rat, induced astroglial expression of tenascin is restricted to the border zone of the lesion. It is interesting to note that the local distribution of tenascin immunoreac-tivity at the lesion site of the transected fornix and the sprouting pattern of the injured axons as shown by Lips et al. (1995) is not compatible with a previously suggested putative axon growth inhibitory function of tenascin in vivo (McKeon et al., 1991). Furthermore, in the tenascin knockout mouse glial scar formation is not altered as compared to wildtype animals (Steindler et al., 1995). 

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