Platelet aggregation onion

Srivastava KC. (1984). Aqueous extracts of onion, garlic and ginger inhibit platelet aggregation and alter arachidonic acid metabolism. Biomed Biochim Acta. 43(8-9) S335-46. 

The effects of onion and garlic on eicosanoid metabolism have mainly been studied by observing the effects of garlic and onion preparations on platelet aggregation and subsequent eicosanoid synthesis. 

The exact mechanism by which garlic oil may suppress Fe-NTA-mediated renal damage is not known. However, onion and garlic extracts have been shown to inhibit platelet aggregation and prostaglandin synthesis. 

Makheja AN, Vanderhoek JY, Bailey JM. Inhibition of platelet aggregation and thromboxane synthesis by onion and garlic. Lancet 1979 1 781. 

Ali M, Bordia T, Mustafa T.Effect of raw versus boiled aqueous extract of garlic and onion on platelet aggregation. Prostagland Leukot Essen Fatty Acids 1999 60(1) 43— 47. 

Srivastava KC. Effects of aqueous extracts of onion, garlic, and ginger on platelet aggregation and metabolism of arachidonic acid in the blood vascular system in vitro study. Prostagland Leukotr Med 1984 13 227-235. 

Among common foodstuffs, onion and garlic have been reported to contain a heat-stable, lipid soluble factor that inhibits platelet aggregation [183-186], This factor inhibits thromboxane synthesis in platelets from exogenous [ C]arachidonic acid. Along with the decreased thromboxane formation, a new metabolite of arachidonic acid appeared, 10-hydroxy-11,12-epoxy-5,8,14-eicosatrienoic acid, probably via the platelet lipoxygenase pathway [185],... 

Garlic and onion are effective for the prevention of thrombosis by inhibiting platelet aggregation (Ariga et al. 2000). Active components have been identified to be allyl methyl trisulfide (Ariga et al. 1981),... 

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