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Omega-conotoxin

Taussig R, Sanchez S, Rifo M, Gilman AG, Delardetti F. Inhibition of the omega conotoxin-sensitive calcium current by distinct G proteins. Neuron 1992 8 799-809. [Pg.484]

GABA = y-aminobutyric acid GVIA = omega-conotoxin GVIA ... [Pg.108]

MVllC = omega-conotoxin NMDA = N-methyl-D-aspartate ... [Pg.108]

Omega conotoxin (co-CTX-GVIA) Blocks N-type channel Pacific cone snail... [Pg.450]

Dubel SJ, Starr TV, Hell J, Ahhjanian MK, Enyeart JJ, Catterall WA, Snutch TP (1992) Molecular cloning of the alpha-1 subunit of an omega-conotoxin-sensitive calcium channel. Proc Natl Acad Sci U S A 89 5058-62... [Pg.66]

Feng ZP, Doering CJ, Winkfein RJ, Beedle AM, Spafford JD, Zamponi GW (2003) Determinants of inhibition of transiently expressed voltage-gated calcium channels by omega-conotoxins GVIA and MVIIA. J Biol Chem 278 20171-8... [Pg.67]

Feng ZP, Hamid J, Doering C, Bosey GM, Snutch TP, Zamponi GW (2001b) Residue Glyl326 of the N-type calcium channel alpha IB subunit controls reversibility of omega-conotoxin GVIA and MVIIA block. J Biol Chem 276 15728-35... [Pg.67]

Olivera BM, McIntosh JM, Cruz LJ, Luque FA, Gray WR (1984) Purification and sequence of a presynaptic peptide toxin from Conus geographus venom. Biochemistry 23 5087-90 Olivera BM, Miljanich GP, Ramachandran J, Adams ME (1994) Calcium channel diversity and neurotransmitter release the omega-conotoxins and omega-agatoxins. Annu Rev Biochem 63 823-67... [Pg.71]

Potier B, Dutar P, Lamour Y (1993) Different effects of omega-conotoxin GVIA at excitatory and inhibitory synapses in rat CA1 hippocampal neurons. Brain Res 616 236 11 Pragnell M, De Waard M, Mori Y, Tanabe T, Snutch TP, Campbell KP (1994) Calcium channel beta-subunit binds to a conserved motif in the I-II cytoplasmic linker of the alpha 1-subunit. Nature 368 67-70... [Pg.71]

Reynolds IJ, Wagner JA, Snyder SH, Thayer SA, Olivera BM, Miller RJ (1986) Brain voltage-sensitive calcium channel subtypes differentiated by omega-conotoxin fraction GVIA. Proc Natl Acad Sci U S A 83 8804-7... [Pg.72]

Scott, D. A., Wright, C. E., and Angus, J. A. (2002). Actions of intrathecal omega-conotoxins CVID, GVIA, MVIIA, and morphine in acute and neuropathic pain in the rat. Eur. J. Pharmacol. 451,... [Pg.259]

Nielsen, K.J., Schroeder, T., Lewis, R. (2000). Structure-activity relationships of omega-conotoxins at N-type voltage-sensitive calcium channels. J. Mol. Recognit. 13 55-70. [Pg.478]

The N-type channel (with the N standing for neither T nor L or neuronal ) appears to convey most of the whole-cell calcium current it is insensitive to dihydropyridine and is blocked by omega-conotoxin. The N-type channel is involved in the release of transmitter in some, but not all, tissues, with the CNS neurons being the exception. [Pg.120]

Ohvera BM, MUjanich GP, Ramachandran J, Adams ME. Calcium channel diversity and neurotransmitter release the omega-conotoxins and omega-agatoxins. Armu Rev Biochem 1994 63 823-67. [Pg.137]

Cohen MW, Jones OT, Angelides KJ. Distribution of Ca channels on frog motor nerve terminals revealed by fluorescent omega-conotoxin. JNeurosci 1991 ll(4) 1032-9. [Pg.138]

Artalejo CR, Perlman RL, Fox AP. Omega-conotoxin GVIA blocks a Ca current in bovine chromaffin cells that is not of the classic N type. Neuron 1992 8(l) 85-95. [Pg.139]

Kasai H, Aosaki T, Fukuda J. Presynaptic Ca-antagonist omega-conotoxin irreversibly blocks N-type Ca-channels in chick sensory neurons. NeurosciRes 1987 4(3) 228-35. [Pg.140]

Turner TJ, Lampe RA, Dunlap K. Characterization of presynaptic calcium channels with omega-conotoxin MVIIC and omega-grammotoxin SIA role for a resistant calcium channel type in neurosecretion. Mol Pharmacol 1995 47(2) 348-53. [Pg.140]

McDonough SI, Swartz KJ, Mintz IM, Boland LM, Bean BP. Inhibition of calcium channels in rat central and peripheral neurons by omega-conotoxin MVBC. J Neurosci 1996 16(8) 2612-23. Newcomb R, Szoke B, Pahna A, Wang G, Chen X, Hopkins W, Cong R, et al. Selective peptide antagonist of the class E calcium channel from the venom of the tarantula Hysterocrates gigas. Biochemistry 1998 37(44) 15353-62. [Pg.141]

Ahmad SN, MUjanich GP. The calcium channel antagonist, omega-conotoxin, and electric organ nerve terminals binding and inhibition of transmitter release and calcium influx. Brain Res 1988 453(l-2) 247-56. [Pg.141]

Farinas 1, Solsona C, Marsal J. Omega-conotoxin differentially blocks acetylcholine and adenosine triphosphate releases from Torpedo synaptosomes. Neuroscience 1992 47(3) 641-8. [Pg.141]

Wessler 1, Dooley DJ, Werhand J, Schlemmer F. Differential effects of calcium channel antagonists (omega-conotoxin GVIA, nifedipine, verapamil) on the electrically-evoked release of [3H acetylcholine from the myenteric plexus, phrenic nerve and neocortex of rats. Naunyn Schmiedebergs Arch Pharmacol 1990 341(4) 288-94. [Pg.141]

Boland LM, Morrill JA, Bean BP. Omega-conotoxin block of N-type calcium channels in frog and rat sympathetic neurons. J Neuro sci 1994 14(8) 5011-27. [Pg.142]

Hofmann F, Habermann E. Role of omega-conotoxin-sensitive calcium channels in inositolphosphate production and noradrenaline release due to potassium depolarization or stimulation with carbachol. Naunyn Schmiedebergs Arch Pharmacol 1990 341(3) 200-5. [Pg.143]

Herdon H, Nahorski SR. Investigations of the roles of dihydropyridine and omega-conotoxin-sensitive calcium channels in mediating depolarization-evoked endogenous dopamine release from striatal slices. Naunyn Schmiedebergs Arch Pharmacol 1989 340(1) 36 0. [Pg.143]

Dooley DJ, Lupp A, Hertting G. Inhibition of central neurotransmitter release by omega-conotoxin GVIA, a peptide modulator of the N-type voltage-sensitive calcium channel. Naunyn Schmiedebergs Arch Pharmacol 1987 336(4) 467-70. [Pg.143]

Rittenhouse AR, Zigmond RE. Omega-conotoxin inhibits the acute activation of tyrosine hydroxylase and the stimulation of norepinephrine release by potassium depolarization of sympathetic nerve ading. JNeurochem 199T,56(2) 615-22. [Pg.144]

Lundy PM, Frew R. Evidence of omega-conotoxin GVlA-sensitive Ca channels in mammahan peripheral nerve terminals. Eur J Pharmacol 1988 156(3) 325-30. [Pg.144]

See other pages where Omega-conotoxin is mentioned: [Pg.329]    [Pg.931]    [Pg.298]    [Pg.517]    [Pg.517]    [Pg.71]    [Pg.260]    [Pg.372]    [Pg.434]    [Pg.517]    [Pg.339]    [Pg.136]    [Pg.280]    [Pg.1070]    [Pg.223]    [Pg.514]    [Pg.138]   
See also in sourсe #XX -- [ Pg.514 ]



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