Oligo dendrimer

Fig. 5. [3]Pseudorotaxane dendrimers from complexation of the dendrophanes and molecular rod with rigid oligo(phenylacetylene) spacers and terminal steroid units... 

Chiral Dendrimers Containing Oligo-(3-Hydroxybutanoate) Units. .139... 

Sato, N., Kobayashi, H., Saga, T., Nakamoto, Y., Ishimori, T., Togashi, K., Fujibayashi, Y., Konishi, J., and Brechbiel, M.W. (2001) Tumor targeting and imaging of intraperitoneal tumors by use of anti-sense oligo-DNA complexed with dendrimers and/or avidin in mice. Clin. Cancer Res. 7, 3606-3612. 

The oligo- or multi-functional core unit also plays a role in determining the space occupied by a dendrimer. The core itself can exercise a function, as demonstrated by metallodendrimers (see Section 4.1.11), in which the metal ion core in a supramolecular or coordinatively constructed architecture coordinates with the surrounding branching units - and in this way can influence catalytic and photochemical processes. 

Follow-on functionalisation with molecular moieties of biological importance, such as anti-tumour agents (e.g. 5-fluorouracil) currently appears particularly attractive. In this context, acetylation is particularly suitable as functionalisation reaction for oligo/polyamine dendrimers. It renders the dendrimers more water soluble, which is essential for biomedical applications [25]. The toxicity of den-... 

Fig. 3.13 Method of local bifunctionalisation of oligo-/polyamine dendrimers...

Divergent synthesis of POPAM dendrimers is based on the concept developed by Vogtle et al. in 1978 (see Section 1.1) [4]. Acrylonitrile is added to a primary mono- or oligo-diamine in a Michael reaction (Fig. 4.2). Suitable reducing agents are Co(II)-borohydride complexes or diisobutylaluminium hydride [5]. Subsequent iterative reaction cycles permit repeated addition of acrylonitrile followed by reduction until the limiting generation is reached. 

Fig. 4.12 Dansyl-decorated oligo-lysine dendrimer (2nd generation) as dendritic antenna with sensor properties towards metal ions (according to Balzani, Vogtle et al)...

Fig. 6.17 POPAM dendrimer with peripheral oligo-ethylene glycol ether units (according to Meijer et al.)...

More examples include the use of Ir(III) complexes in dendrimers [136] and as pendants in oligo- or polymeric lluorene (or carbazole), in part already discussed in Sect. 3.4 [76,137,138]. Both cases illustrate viable methods to solve the problem of phase separation in electroluminescent polymers doped with Ir(III) complexes and are not treated here in detail. 

The use of dendrimers as supports for homogeneous catalysts was first reported by van Leeuwen and coworkers in 1995 (122). Oligo-carbosilane dendrimers were developed for this purpose (123). The open structure and solubility of dendrimers allow the attached catalysts to behave like... 

Fig. 7 Chemical structures of poly(oligo(ethylene glycol) [poly(OEGMA)] methacrylate) (A) 5-arm star-shaped poly(OEGMA) (B) and polyglycerol dendrimers with generation 3 (C) 4 (D) and 5 (E). (Modified from Ref l)...

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