Secoiridoids from Oleaceae

The tables 1 - 7 contain the structures of the iridoids and secoiridoids from Oleaceae. The reference and the natural origin correspond to the first cite in which the compound has been named. In any case, secoiridoids such as oleuropein (81), ligustroside (82) and many others can be obtained from several species. 

The secoiridoids from Fontanesia differ from those found in other genus of Oleaceae. The typical secoiridoids derived from oleoside 78 are absent but, in their place, others derivatives closer to secologanic acid, very similar to those of Gentiales, are present. Damtoft and col. [102]... 

Frederickson, W. R. Antiviral compositions comprising secoiridoids obtained from Oleaceae. Patent-PCT Int Appl -96 14,064 1996 20 pp. Carmena, R., J. F. Ascaso, G. Camejo, et al. Effect of olive and sunflower oils on low density lipoprotein level, composition, size, oxidation and interaction with arterial proteoglycans. Atherosclerosis 1996 125(2) 243-255. Yaqoob, P., J. A. Knapper, D. H. Webb, C. M. Williams, E. A. News-holme, and P. C. Calder. Effect of olive oil on immune function in middle-... 

Oleuropein, a secoiridoid glycoside Fraxinus excelsior (ash tree), Olea europaea (olive tree) and Ligustrum obtusifolium from the family Oleaceae are the major sources of oleuropein. This compound has hypotensive. 

When the crude secoiridoid glucoside mixture derived from the fruits of Ligustrum vulgare (Oleaceae) was treated with 5% sulfuric acid and then with ammonia, TLC analysis revealed the presence of 12 alkaloid-positive spots (29). No alkaloids were detected in the absence of ammonia. Four of these alkaloids were characterized. One was identical with jasminine (97) the other three isolates were new. 

Iridoids and secoiridoids show a wide variety of biological and pharmacological activities which have been reviewed by Ghisalbert [6] up to 1998. We report here a review of the most relevant compounds of this type isolated from Oleaceae. 

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