Nutrients and gene expression

Mark M, Ghyselinck NB, Wendling O, Dupe V, Mascrez B, et al. 1999. Symposium on Functionality of nutrients and gene expression . A genetic dissection of the retinoid signaling pathway in the mouse. Proc. Nutr. Soc. 58 609-13... 

Nutrients and Gene Expression Clinical Aspects, Carolyn D. Berdanier... 

De Caterina, R, Madonna, R, Hassan, J, and Procopio, AD, Nutrients and gene expression. World Rev Nutr Diet, 2001. 89 23-52. 

These questions are amenable to various combinations of imaging, modelling, metabolic and gene expression studies and field observation to analyse the nutrient dynamics of the forest floor microbial decomposer subsystem, and to provide data for predictive models of forest floor responses to environmental change. 

Studies performed in vitro with cells growing on a two-dimensional surface have observed isolated cell function performance, such as proliferation, glycolysis, respiration, and gene expression, by optimizing the media nutrient, hormone, and growth factor compositions. However, the proper regulation and control of these functions are dependent on cellular interactions... 

Our studies of the ERT cell cycles show that they are regulated by nutrition (Britton Edgar 1998). If the newly hatched larva is starved for dietary amino acids, DNA replication in most ERTs is not initiated. Under starvation conditions these tissues express low levels of cyclin E and E2F, the transcription factor which is probably responsible for cyclin E expression. If either E2F or cyclin E is induced in starved larvae, DNA replication in the ERTs is activated, and thus expression of these genes appears to limit the ERT cell cycle. When nutrient-deprived larvae are fed, expression of E2F and cyclin E mRNAs increases approximately sixfold, and DNA replication is initiated in most ERT cells. If the animal is first fed and then starved, the ERT cell cycle is activated and then inactivated quite rapidly. These experiments all indicate that the ERT cell cycle is nutrition-responsive, rather than controlled by a rigid developmental program. 

Yamada, K. Noguchi, T. (1999) Nutrient and hormonal regulation of pyruvate kinase gene expression. Biochem J. 337, 1—11. Detailed review of recent work on the genes and proteins of this system and their regulation. 

Lillo C, Lea US, RuoffP. 2008. Nutrient depletion as a key factor for manipulating gene expression and product formation in different branches of the flavonoid pathway. Plant Cell Environ 31 587-601. 

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