Nucleophiles formation

Stabilized enolate anions as nucleophiles formation of carbon-carbon bonds (P condensation)... 

Buscemi, S., Vivona, N. and Caronna, T. (1996) Photoinduced molecular rearrangements. The photochemistry of some 1,2,4-oxadiazoles in the presence of nitrogen nucleophiles. Formation of 1,2,4-triazoles, indazoles, and benzimidazoles. Journal of Organic Chemistry, 61 (24), 8397-8401. 

The allylation of imines with allylindium reagents in organic solvents gives the corresponding homoallylic amines.251-253 Under solvent-free conditions, the indium-mediated reaction of iV-benzylideneaniline furnishes a mixture of mono-allylated 79 and bis-allylated products 80 (Equation (56)). The bis-allylated product 80 presumably arises via a formation of an iminium salt, which is subsequently attacked by the allylindium nucleophiles. Formation of 80 is entirely suppressed by addition of allyl bromide to indium metal prior to any addition of the imine (Grignard-type reaction).254... 

Stankovicova, H., Fabian, W. M. F., Lacova, M. Synthesis and theoretical study of Mannich type reaction products of 3-formylchromones with triazoles and amides and nucleophilic formation of 2,3-disubstituted-4-chromanones. Molecules [Electronic Publication] 1996,1, 223-235. 

Reactions with nucleophiles, formation of acidic species)... 

Table 2 Reactions of nitrile ligands with protic nucleophiles formation of C—O bond.

Hexafluoropropene oxide is also a good reagent for the nucleophilic formation of the Bi-F bond in triphenylbismuth) V) compounds [99JFC(93)103],... 

Replacement of sodium azide by other nucleophiles (formates, acetates, benzoates, or cyanates) gives the elimination derivative as the major reaction... 

Nucleophilic addition of carbon nucleophiles formation of C C bonds... 

Nucleophilic addition of oxygen nucleophiles formation of hydrates and acetals... 

Nucleophilic addition of sulfur nucleophiles formation of thioacetals... 

Nucleophilic addition of amine nucleophiles formation of imines and enamines... 

Deprotonation of the a-carbon of the ketone by ethoxide to make an enolate whose carbon does an Sjj2 displacement of chloride from chloroacetonitrile, followed by intramolecular nucleophilic formation of the epoxide ring in structure E. 

The Johnson group began by examing the solvolysis of 5-hexenyl nosylate (65) in formic acid. This reaction gave only small amounts of cyclohexanol and cyclohexene, but illustrated that that cyclization was possible. Solvolysis of diene 66 gave cyclohexanol 67 as the major product. This product results from addition of the electrophilic carbon (Ci) and oxygen nucleophile (formate) across the fm r-olefin. Decalins 68-70 were produced in low yields, but it was notable that only fm -fused decalins were produced. This observation was consistent with an addition of electrophilic carbon (Ci) and nucleophilic carbon (Cio) across the af-olefin (see B in Steroids-12). 

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