Nuclear transfer technology

A number of alternative approaches are being developed that may overcome some of these issues. Replication-defective retroviral vectors are available that will more consistently (a) deliver a chosen gene into cells and (b) ensure chromosomal integration of the gene. A second innovation is the application of nuclear transfer technology. 

BOX 15.1. BASIC CONCEPT OF NUCLEAR TRANSFER TECHNOLOGY IN ANIMAL CLONING... 

Over the past decade, significant progress has been made in stem cell research the derivation of ESCs from human blastocysts [9], the development of somatic cell nuclear transfer technology [10] and the confirmation that neurogenesis occurs in the adult... 

Researchers at Scotland s Roslin Institute reported that they had cloned a sheep-named Dolly-from the cell of an adult ewe. Polly, the first sheep cloned by nuclear transfer technology bearing a human gene, appeared later... 

Rohricht P, Ayares D. Transgenic Protein Production Part 3, Nuclear Transfer Technology. BioPharm, 1999 56-60. 

Pebble-Bed Modular Reactor (PBMR) A nuclear reactor technology that utilizes tiny silicon carbide-coated uranium oxide granules sealed in pebbles about the size of oranges, made of graphite. Helium is used as the coolant and energy transfer medium. This containment of the radioactive material in small quantities has the potential to achieve an unprecedented level of safety. This technology may become popular in the development of new nuclear power plants. 

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