Nuclear Magnetic Resonance metabonomics application

Solanky, K.S. et al., Application of biofluid IH nuclear magnetic resonance-based metabonomic techniques for the analysis of the biochemical effects of dietary isoflavones on human plasma profile. Anal. Biochem., 323, 197, 2003. 

Since laboratory measurements commenced, we have used biomarkers however, in the last decade there has been a great deal of discussion and debate about the term biomarker, its definition, and its usage (Colburn 1997 Biomarkers Definitions Working Group 2001 Frank and Hargreaves 2003). The term biomarker is often used to encompass relatively new indices—for example, plasma and urine profiles obtained with nuclear magnetic resonance spectroscopy (NMR), metabonomics, proteomics, etc. (Grandjean et al. 1994 Timbrell, Draper, and Waterheld 1994). However, the term is equally applicable to the traditional core tests. 

H.-c. Gao and D.-h. Lin, Applications of Nuclear Magnetic Resonance Spectroscopy and Nuclear Magnetic Resonance-Based Metabonomics in Tumour Studies , Zhongguo Yixue Kexueyuan Xuebao, 2007, 29, 803. 

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