Novobiocin chemical structure

Fig. 3.9 Chemical structures of colistin, polymyxin, rifaximin, rifamycin SV, novobiocin, and tiamulin.

Novobiocin (I) is the official name given to an antibiotic discovered by no fewer than five independent groups of workers [1-5]. It is a dibasic acid, and before its chemical structure was completely elucidated it was defined as... 

It is not possible, therefore, to attribute the major effects of novobiocin to any particular part of its unique chemical structure, the intact molecule being necessary for full activity. 

Chemically, novobiocin has a unique structure among antibiotics. though, like. several others, it possesses a glyeosidie sugar moiety. The sugar in novobiiK in. devoid of its eurba-... 

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