Nothogenia fastigiata

Seaweed Various sulfated polysaccharides extracted from seaweed (i.e., Nothogenia fastigiata, Aghardhiella tenera) inhibit the virus adsorption process. 

The a-(1 3)-hnked D-mannans of Nothogenia fastigiata sulfated on C-2 and C-6 also mimic the minimal binding domain of HS. However, the lower antiviral activity of the fractions with D-xylose side chains suggests that branching precludes binding to the gC viral protein [21],... 

Y. Fukuyama, A. D. Kolender, M. Nishioka, H. Nonami, M. C. Matulewicz, R. Erra-Balsells, and A. S. Cerezo, Matrix-assisted ultraviolet laser desorption/ionization time-of-flight mass spectrometry of / -(l—>3), f-( 1 —>4)-xylans from Nothogenia fastigiata using nor-harmane as matrix, Rapid Com-mun. Mass Spectrom., 19 (2005) 349-358. 

A. A. Kolender, C. A. Pujol, E. B. Damonte, M. C. Matulewicz, and A. S. Cerezo, The system of sulfated alpha-(l—>3)-linked D-mannans from the red seaweed Nothogenia fastigiata Structures, antiherpetic and anticoagulant properties, Carbohydr. Res., 304 (1997) 53-60. 

Examples of sulphated PS with anti-HIV activity also included sulphated a-D(l—>3)-linked mannans from Nothogenia fastigiata [24], from Schizymenia dubyi [25], anti-HIV PS from the brown seaweed Fucus vesiculosus [26] and from the marine microalga Cochlodinium polykrikoides [27]. Sulphated PS displaying antiviral activities against HIV-1 and human immunodeficiency virus type 2 (HIV-2) were also isolated from marine Pseudomonas and Dinoflagellata [28]. 

Other anti-HSV sulphated PS included sulphated galactans from the marine alga Bostrychia montagnei [89], the red seaweed Pterocladia capillacea [90], extracts of Cryptopleura ramosa and Nothogenia fastigiata, two red seaweeds from the South American coast [91,92], and fucoidans from the brown seaweed utricularis [93]. 

Sulfated polysaccharide fraction Exerted activity against HSV-2, HCMV, RSV, influenza A and B virus Nothogenia fastigiata Damonte et al. (1994)... 

Other types of sulfated polysaccharides from red algae have been studied for their antiviral activities, particularly that of a sulfated a-o-(l 3)-xylomannan from the red alga Nothogenia fastigiata, Nemaliales (Damonte et al., 1994 Kolender, Matulewicz, and Cerezo, 1995 Kolender et al, 1997). 

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