Normal Lymphoid Cell Development and Antigen Expression

Normal Lymphoid Cell Development and Antigen Expression 

Lymphoid neoplasms in both the REAL and the WHO classifications are defined as specific entities based on morphology, immunophenotype, genotype, and clinical characteristics (HI 1, J2). These neoplastic entities, however, tend to mimic their 

B Cell Differentiation Immunophenotypic Profiles of Normal B Lymphoblasts 

Misc Maybe cCD79a sCD20 late in stage Maybe CD34 c/t 

T cell development, similar to B cell ontogeny, can also be divided into stages based on antigen expression (Table 4) extrathymic precursor, prothymocyte, immature thymocyte, common thymocyte, mature thymocyte, and mature peripheral T cell. However, while the early stages of T cell development are well characterized, the later stages of T cell differentiation, that is, those of the mature peripheral T cell, have not been fully delineated (C3, F12, H13, K15, K16, K20, R6-R8,V3, V4). Furthermore, although natural killer (NK) cells are closely related to T cells (S21), the stages of differentiation of this lymphoid cell population are not completely understood. 

---

Normal Lymphoid Cell Development and Antigen Expression. 303... 

---