Nonionic hydrophilic cream

Figure 18 Influence of different cream bases on the photostability of Retinoic Acid. A, Basis cream DAC B, hydrophilic ointment with water DAB C, nonionic hydrophilic cream DAB ...

Hydrophilic cream 0/w cream Nonionic hydrophilic cream SR DAC (Table 12.33), Lanette cream I and II (Table 12.34)... 

The formulation in Table 12.33 represents a non-ionic-active hydrophilic cream base. It contains a liquid wax (ethylhexyl laurate), which is well absorbed by the skin. The robust cream base tolerates processing of organic solvents and of phenols such as salicylic acid, in spite of its nonionic character. Lanette creams 12.34 are anionic-active bases. The two formulations differ in their consistency. The higher amount of emulsifying cetostearyl alcohol in Lanette cream II leads to a more stiff cream. It is especially suitable for preparations with a larger quantity of liquids. 

Properties Oil nonionic Uses Bioavailability enhancer, emulsifier, solvent, solubilizer for cosmetic, pharmaceutical, and veterinary creams, lotions, ointments, shampoos, bath oils Features Hydrophilic... 

The theory of this four-phase system (hydrophilic gel phase, lipophilic gel phase, filling water phase and disperse inner phase) generally applies to o/w creams prepared with ionic or nonionic emulsifiers and to stearate creams [3]. 

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