Noncollagenous proteins

Masters, P.M. 1987 Preferential preservation of noncollagenous protein during bone diagenesis Implications for chronometric and stable isotopic measurements. Geochimica et CosmochimicaActa 51 3209-3214. 

As discussed earlier, noncollagenous proteins, particularly albumin and to a lesser extent gelatin, in the form of microspheres and nanoparticles continue to be exploited as drug delivery systems. Oppen-heim (71) and Speiser (72) reviewed the technology developed to produce ultrafine particles, often referred to as nanoparticles. 

Noncollagen proteins Plasma proteins Mixture of various plasma proteins. 

Dimuzio, M. T., Veis, A. Phosphoryns-major noncollagenous proteins of rat incisor dentin. Calc. Tiss. Res. 25, 169 (1978)... 

A key to the development of osteoblasts appears to be an osteoblast-specific transcription factor OS/2 or Cbfal.693-695 Mutations in human Cbfal are linked to a series of skeletal defects.696 A unique change accompanying conversion of a precursor cell into an osteoblast is the formation of a 49-residue y-carboxyglutamate (Gla)-containing protein called osteocalcin.697 (See also Box 15-F). It is the most abundant noncollagenous protein of bone. Its three Gla residues doubtless help to bind calcium ions and osteocalcin may be an initiator of crystallization. Osteocalcin has also been found in fish scales.698 Also present in bone is a 74-residue matrix Gla protein which has 5 Gla residues.699... 

Laminin [consisting of three polypeptide chains, A, Bl (possibly replaced in GBM by S) and B2] is the most important noncollagenous protein of the glomerular basement membrane. Laminin forms a second network, which is connected to the collagen IV network probably via another protein called entactin or nidogen. Laminin is probably very important for cellular differentiation and adhesion, but its mesh clearly also contributes to the structure of the glomerular basement membrane. The postnatally common embryonic laminin-10 isoform is... 

Collagen and the noncollagenous proteins were isolated by the general procedure indicated in Figure 1. The tissue was homogenized in... 

Residue (noncollagenous protein) washed with 95% ethanol... 

Table II. Incorporation of C14-Tryptophan into Collagen and Noncollagenous Proteins of Guinea Pig Granuloma...

Which of the following statements about noncollagenous proteins of connective... 

The framework contains many other proteins, polysaccharides and lipids, in addition to collagen. These include noncollagenous proteins (NCPs) and proteoglycans that are also present in bone, lipids and proteins present in serum, as well as dentin-specific proteins [25, 27]. The dentin-specific NCPs are rich in aspartic acid and the amino acid phosphoserine. The sequences of some of these proteins have been determined, revealing large stretches of repeating... 

Noncollagenous proteins also show variable preservation between samples from a single archaeological site. Gel electrophoresis (Fig. 2) of human bone extracts from the 7000-year-old Windover site exhibited a... 

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