Non-hemiterpenoid Quinolines

Non-hemiterpenoid Quinolines.—A re-examination of the alkaloids of Haplophyllum dubium resulted in the isolation of two members of the 2-aryl-4-quinolone group, i.e. graveoline (2 R = Me) and the new alkaloid norgraveoline (2 R = H).5 A new bacterial pseudan (3) has been obtained from Pseudomonas aeruginosa.8 

Yajima, N. Kato, and K. Munakata, Agric. Biol. Chem., 1977, 41, 1263. 

Mester, J. Reisch, K. Szendrei, and J. Korosi, Liebigs Ann. Chem. 1979, 1785. 

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Non-hemiterpenoid Quinolines.—New sources of the simple quinolines 4-methoxy-l-methyl-2-quinolone and its 8-methoxy-derivative (folimine) have been reported the former was isolated from Myrtopsis sellingii9 and from Zanthoxylum cuspidatum,16 and folimine was shown to be a constituent of Haplophyllum perforatum.5 The latter species also contains foliosidine (9), previously isolated from H. foliosum. The micro-organism Pseudomonas aertiginosa has been shown to contain 2-(hept-l-enyl)-4-quinolone (12).10 The structure of the alkaloid was established by n.m.r. and mass spectroscopy and by its synthesis from aniline and the j3-keto-ester Me(CH2)4CH=CHC0CH2C02Me. 

Non-hemiterpenoid Quinolines.—The three non-hemiterpenoid quinoline alkaloids reported this year are all 3-metho iyquinoline derivatives. Furoquinoline alkaloids had been isolated previously from Chloroxylon swietenia (East Indian satin wood), but now two new alkaloids, swietenidins A and B, have been obtained from the bark. Spectroscopic studies of swietenidin A and its monomethyl ether, and comparison of the data with those of the known 8-methoxy-iV-methyl-2-quinolone lunacridine, indicated that the alkaloid was the... 

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