Nomenclature, fluorinated heterocycles

Heterocycles containing limited amount of fluorinated substituents (usually 1-3) can be named using trivial names or conventional nomenclature in combination with indication of the position of fluorinated substituents, for example, 2-fluoro-4-tri-fluoromethylpyridine. The situation becomes more complicated in case of poly-fluorinated and completely fluorinated heterocycles. In case of heterocycles with relatively small number of fluorinated substituents and well-defined stmctures, Greek or Latin numeral roots can be used. Names such as hexafluoropropene oxide, 2,2-bis (trifluoromethyl)oxirane, 2,2,3,3-tetrafluorooxetane, tetrakis(trifluoromethyl)furane, pentafluoropyridine, tetrafluoropyridazine, tetrafluoropyrimidine, and heptafluoro-quinoline are unambiguous and commonly accepted (see Fig. 0.1). 

Heptafluoroquinoline FIGURE 0.1 Nomenclature of poly fluorinated heterocycles. 

FIGURE 0.2 Examples of perfluoro- and F-nomenclatures of fluorinated heterocycles. 

It should be pointed out that for completely fluorinated materials, one could use the so-called perfluoro- or F-nomenclature. The prefix perfluoro- or symbol F- have the same meaning and combined with trivial or standard systematic name of a heterocycle, it indicates that in parent compound all hydrogens connected to carbons were replaced by fluorines. Examples of different names for heterocycles, such as per-fluoropropene oxide or F-propene oxide, perfluoro-(2,2-dimethyloxirane) or F-(2,2-dimethyloxirane), and so on, are shown in Fig. 0.2. 

---

See also in sourсe #XX -- [ ]

---