NodD gene

H. P. Spaink, C. A. Wijffelman, R. J. H. Okker, and B. J. J. Lugtenberg, localization of the functional regions of the Rluzobium NodD product, using hybrid nodD genes. Plant Mol. Biol. 12 59-73 (1986). 

Horvath B., Bachem, C.W.B., Schell, J. Kondorosi, A. (1987). Host-specific regulation of nodulation genes in Rhizobium is mediated by a plant-signal interacting with the nodD gene product. The EM BO Journal 6, 841-8. 

Hartwig, U. A., C. A. Maxwell, C. M. Joseph, and D. A. Phillips, Effects of alfalfa nod gene-inducing flavonoids on nodABC transcription in Rhizobium meliloti strains containing different nodD genes, J. Bacteriol., 172, 2793-2773 (1990a). 

The nodD gene initially was thought to be a common nod gene (Downie and... 

Spaink, H.P. et al., Rhizobium nodulation gene nodD as a determinant of host specificity, Nature, 328, 337, 1987. 

Other Nod genes provide for modifications that restrict infection to specific species of legumes. For example, nodS encodes a methyltransferase and nodU a carbomoyltransferase.65 NodH is a sulfotransferase.66 NodD is a transcriptional activator that binds to DNA and induces the synthesis of the other Nod factors needed to initiate nodulation.67 When an appropriate Nod factor is recognized, the root hairs on the legume... 

Fig. 2. Identification and organization of the symbiotic genes on plasmids of Rhizobium meliloti and Rhizobium leguminosarum. Note the difference in proximity ofN(fK,D,H tofixA,B,C,X in R. meliloti as compared to R. leguminosarum. Other features of interest include three copies of the nodD regulatory gene found in R. meliloti and a second fix region located some 200 kb away fixjm the 60-kb symbiotic gene cluster of R. meliloti.

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