NMDS

NMD(1,J) cols 1-6 six-character identification code for component one this must match the code read in with the pure-component data. 

NMD A receptors are selectively activated by A/-methyl-D-aspartate (NMD A) (182). NMD A receptor activation also requires glycine or other co-agonist occupation of an allosteric site. NMDAR-1, -2A, -2B, -2C, and -2D are the five NMD A receptor subunits known. Two forms of NMDAR-1 are generated by alternative splicing. NMDAR-1 proteins form homomeric ionotropic receptors in expression systems and may do so m situ in the CNS. Functional responses, however, are markedly augmented by co-expression of a NMDAR-2 and NMDAR-1 subunits. The kinetic and pharmacological properties of the NMD A receptor are influenced by the particular subunit composition. 

NMD A, kainic acid, and AMPA, are stimulants and convulsants (14). These agents are used only experimentally. 

Cell Chemistry. Work on the mechanism of the carbon—2inc cell has been summari2ed (4), but the dynamics of this system are not entirely understood. The electrochemical behavior of electrolytic (FMD), chemical (CMD), and natural (NMD) manganese dioxide is slightly different. Battery-grade NMD is most commonly in the form of the mineral nsutite [12032-72-3] xMn02, which is a stmctural intergrowth of the minerals... 

Table 4 shows //(ApH) at the 7 mAh stage. We can see that //(ApH) is very small for CMD and nonporous manganese dioxide (NMD). This is very reasonable since the pore diameter of CMD and NMD is much bigger than that of EMD. This is why EMD for ZnCl2 cells is usually produced at high current, in order to increase its pore dimensions. 

Chen L, Huang LY Sustained potentiation of NMD A receptor-mediated glutamate responses through activation of protein kinase C by a mu opioid. Neuron 7 319-326, 1991... 

There have been a number of observations which show increased excitation and/or reduced inhibition in slices prepared from human epileptic brain tissue. Thus burst discharges can be evoked with stimuli that would not do so in normal animal tissue and these can be blocked by NMD A receptor antagonists. The inhibitory postsynaptic currents (IPSCs) in hippocampal dentate granule cells in slices prepared from temporal lobe epileptic tissue are in fact reduced by stimulation that activates NMDA currents (Isokawa 1996), which are more prolonged than usual and show changes in slope conductance. 

Stelzer, A, Slater, NT and Bruggencate, G (1987) Activation of NMD A receptors blocks GABA ergic innervation in an in vitro model of epilepsy. Nature 326 698-701. 

Scheme 12.3 Formation of dihydride intermediates of a cationic Rh complex via displacement of the NMD ligand in the DIPHOS-derived catalyst (S = solvent).

By using the external SNR52 promoter and the NMD-deficient upfl A strain, the overall purified yields of unnatural amino acid-containing proteins have reached 15 mgl of yeast cells, 300-fold higher than the... 

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