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NMDA glycine

Felbamate Felbatol NMDA glycine site, GABA... [Pg.211]

Bordi, F. and Quartaroli, M. Modulation of nociceptive transmission by NMDA/glycine site receptor in the ventroposterolateral nucleus of the thalamus. Pain 2000, 84, 213-224. [Pg.414]

NMDA glycine-site antagonists <03BMCL3553>, 5-aryl-pyrazolo[3,4-6]pyridazines as inhibitors of glycogen synthase kinase-3 <03BMCL1581>, and 3-arylamino- and 3-cycloalkylamino-5,6-diphenylpyridazines as ACAT inhibitors <03AP563>. [Pg.352]

Pharmacology and Mechanism of Action. Felbamate appears to act as an antagonist of the glycine receptor site on the V-methyl-D-aspartate (NMDA) receptor. This action inhibits the initiation and propagation of seizures. It also may inhibit NMDA/glycine-stimnlated increases in intracellular Ca . ... [Pg.1037]

Nagata R, Katayama S, Ohtani K et al (2006) Tricyclic quinoxalinediones, aza-kynurenic acids, and indole-2-carboxylic acids as in vivo active NMDA-glycine antagonists. Curr Top Med Chem 6 733-745... [Pg.132]

Ion channels consist of homo-or heteromeric complexes numbering between three (P2X) and eight (Kirs) subunits. Examples of these are the GABA /benzodiazepine and NMDA/ glycine receptor, neuronal nicotinic receptors (nAChR), and P2X receptors. [Pg.333]

Keywords NMDA Glycine antagonists Stroke Indole-2-carboxylates Benzoazepines Pyrido[2,3-()]pyrazines... [Pg.170]

J.L. (2008) Discovery of NMDA glycine site inhibitors from the chemical universe database GDB. ChemMedChem, 3, 1520-1524. [Pg.32]

Other applications of similar couplings include the synthesis of tricyclic indole-2-carboxylic acids as N-methyl-D-aspartate (NMDA)-glycine antagonists [97] and 10-deoxyartemisinins against malaria [98]. [Pg.152]

Katayama, S., Ae, N. and Nagata, R. (2001) S3mthesis of tricyclic indole-2-carboxylic acids as potent NMDA-glycine antagonists. J. Org. Chem., 66, 3474-83. [Pg.162]

See other pages where NMDA glycine is mentioned: [Pg.922]    [Pg.321]    [Pg.746]    [Pg.283]    [Pg.283]    [Pg.287]    [Pg.388]    [Pg.389]    [Pg.67]    [Pg.69]    [Pg.515]    [Pg.233]    [Pg.154]    [Pg.176]    [Pg.72]    [Pg.16]    [Pg.120]    [Pg.132]    [Pg.104]    [Pg.104]    [Pg.335]    [Pg.8]    [Pg.8]   


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Glycine NMDA receptors

Glycine/NMDA antagonists

NMDA

NMDA Receptor Glycine-site Agonists

NMDA glycine-site agonists

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