Nitroglycerin interactions

Chong, S., Fung, H-L., Biochemical and pharmacological interactions between nitroglycerin and thiols. Effects of thiol structure on nitric oxide generation and tolerance reversal. Biochem. Pharmacol. 42 (1993), p. 1433-1439... 

Drugs that may interact include cephalosporins, nitroglycerin, penicillins, and salicylates. 

Drugs that may interact with labetalol include beta-adrenergic agonists, cimetidine, glutethimide, halothane, and nitroglycerin. 

The mechanism of action of nitroglycerin and other organic nitrates is thought to involve an interaction with nitrate receptors that are present in vascular smooth muscle. Intact vascular endothelium is not necessary for... 

Certain vasodilators (like nitroglycerine) and hormones which can penetrate the buccal mucosal wall will only be kept in buccal cavity or under the tongue. It provides rapid onset of action and prevention of gastrointestinal interactions. 

Fung, H.-L., Yap, S. K., and Rhodes, . T. (1974), Development of a stable sublingual nitroglycerin tablet. I. Interaction of nitroglycerin with selected macro-molecules, /. Pharm. Sci., 63,1810. 

To decide whether a given mixture is suitable for filling shells or for producing non-freezing dynamites. Thermal analysis of the components of mixtures in practical use, e.g. nitroglycerine and centralite, fulfils a similar, practical aim by explaining the interaction of these substances, in particular whether they form simple eutectics, molecular compounds or solid solutions. 

NO synthase is activated in response to Ca2+, which is released in the endothelial cells in response to acetylcholine or bradykinin interaction with their respective cell surface receptors. The NO synthesized diffuses into smooth muscle cells of the blood vessels causing them to relax. Nitroglycerin, a drug used to treat angina pectoris patients, causes vasodilation by giving rise to NO. 

Explosive material with low rate of combustion. May be either solid or liquid. Will burn smoothly at uniform rate after ignition without depending on interaction with atmosphere. Single base propellant consists primarily of matrix of nitrocellulose. Double base propellant contains nitrocellulose and nitroglycerine. Composite propellant contains oxidizing agent in matrix of binder. 

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