4’-nitroacetophenon

O-Bromo-4-nitroacetophenone [99-81-0] M 244.1, m 98°. Crystd from "CgHs-pet ether. 

Nitroacetophenone 100-19-6) M 165.2, m 80-81", b 145-152"/760mm. Crystd from EtOH or aqueous EtOH. 

The catalyst used throughout this study was a 1% w/w palladium on graphite powder (S.A. 10 mV ) supplied by Johnson Matthey. 2-nitroacetophenone, 3-nitroacetophenone and 4-nitroacetophenone (all Aldrich >99 %) were used without further purification. No significant impurities were detected by GC. Gases (BOG, >99.99 %) were used as received. 

Preferential reduction of a nitro group in the presence of a carbonyl group in 4-nitroacetophenone ISD, intramolecular rearrangements of o-nitro-benzanilides 32) intramolecular cyclizations of o-nitro-ferf-anilines to benzimidazol-1-oxides 153,154) cyclizations of acylated 2-nitrodiphenylamines to phenazine-l-oxides i ), intramolecular additions of nitro groups to double bonds 156) remarkably ef-... 

The use of dinitrogen pentoxide in the Ponzio reaction for the oxidation-iutration of oximes to em-dinitro groups has been reported by Russian chemists. Millar and co-workers extensively investigated these reactions and reported the synthesis of 2,4,5,7,9,9-hexanitrofluorene (2), a thermally stable explosive with an oxygen balance better than TNT. Other energetic materials containing gem-dinitro functionality were synthesized from the oximes of acetophenone, 4-nitroacetophenone, a-nitroacetophenone and 2-hydroxyacetophenone. 

They were found not to react with BESOD, the rate constant was estimated to be < 10 M s , if there was a reaction at all The reaction of BESOD was also investigated with several other radicals generated by pulse radiolysis. With the semiquinone of riboflavin 5 -phosphate no reaction was detected. The semiquinone of 9,10-anthraquinone-2-sulfonate and the radical anion of 4-nitroacetophenone converted the enzyme into an unreactive form... 

As seen in Table XIII, the yield of 2-aryl-1-vinylpyrroles depends much on the benzene ring substituent. The sharp decrease in the yield of 4-bromophenyl-l-vinylpyrrole (from 4-bromoacetophenone oxime) is expected it is caused by reaction at the bromine atom with the strong base. No success was attained in an attempt to obtain pyrrole from 4-nitroacetophenone oxime under the conditions studied as a result of instability of the substituent in the super base medium. 

Abbreviations ABTS = 2,2 -azinobis(3-ethylbenzothiazoline-6-sulfonate ion) AH2 = ascorbic acid = 1,1 -dimethyl-4,4 -bipyridinium PNAP = 4-nitroacetophenone PZId" " = prome-... 

The chemoselective reduction of nitro and carbonyl functions with /-PrOH/ KOH over nickel-stabilized zirconia has recently been reported by Upadhya et al. [10]. This catalytic system selectively reduced 4-nitroacetophenone and... 

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