Nitric oxide electrochemical sensors sensitivity

A library of 83 metalloporphyrins was generated by parallel synthesis.75 The substitution pattern was varied at the meso position of the porphyrines, and the central metal ions were altered (Table 14.3). To investigate the use of the members of the library as electrocatalytic material for sensitive sensors for nitric oxide (NO), a complex assay sequence was fulfilled by means of the electrochemical robotic system (Fig. 14.24). In first step, residual water was removed... 

Shioya. T. Swager, T.M. A reversible resistivity-based nitric oxide sensor. Chem. Commun. 2002. 1364-1365. Takenaka. S. Highly sensitive probe for gene analysis by electrochemical approach. Bull. Chem. Soc. Jpn. 2001, 74. 217-224. 

Nitrite Nitrite is an important indicator of fecal pollution in natural waters as well as a potential precursor of carcinogenic species. A rush of flow and sequential injection spectrophotometric method based on Griess-type reactions has been proposed, also coupled to online sorbent enrichment schemes. The catalytic effect of nitrite on the oxidation of various organic species constitutes the basis of fairly sensitive spectrophotometric methods. Fluorometric methods based on the formation of aromatic azoic acid salts, quenching of Rhodamine 6G fluorescence, and direct reaction with substituted tetramine or naphthalene species have been also reported. Indirect CL methods usually involve conversion into nitric oxide and gas-phase detection as mentioned in the foregoing section. The redox reaction between nitrite and iodide in acidic media is the fundamental of a plethora of flow injection methodologies with spectrophotometric, CL, or biamperometric detection. New electrochemical sensors with chemically modified carbon paste electrodes containing ruthenium sites, or platinum electrodes with cellulose or naphthalene films, have recently attracted special attention for amperometric detection. 

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