Nitric oxide chemistry

Garrel, C. Fontecave, M. Nitric oxide chemistry and biology, Analysis of Free Radicals in Biological Systems Eds. Favier, A. E. Cadet, J. Kalyanaraman, B. Fontecave, M. Pierre, J.-L. Birkhauser Verlag Basel, 1995, pp. 21-35. 

Fukuto JM, Ignarro LJ. (1997) In vivo aspects of nitric oxide chemistry Does peroxynitrite play a major role in cytotoxicity. Ace Chem Res 30 149-152. 

NITRIC OXIDE CHEMISTRY AND BIOACTIVITY IN ANIMAL AND PLANT CELLS... 

Nitric oxide chemistry and bioactivity in animal and plant cells 909... 

This quite general and highly selective introduction on nitric oxide chemistry had the aim to stress the importance of reviewing the organometallic and coordination chemistry of NO, whenever this molecule may get connected to a function in homogeneous catalysis. This chapter will describe well-established examples of the versatility of nitrosyl-based homogeneous catalyses and maybe it will help to identify nitrosyl niches worth for exploitation and development to accomplish new and better performing transition metal catalysts, in particular those with middle transition elements. 

Richter-Addo GB, Legzdins P, Burstyn J (2002) Introduction nitric oxide chemistry. Chem Rev 102 857-859... 

At high flame temperatures, small amounts of nitrogen react with oxygen to form nitrogen oxides, NO, primarily nitric oxide, NO. The chemistry of these nitrogen oxides is complex. Ultimately, however, some form nitrosylsulfuric acid, which ends up either as trace amounts in product acids or, in considerably higher concentrations, as condensed acid collected at mist eliminators. 

Nitric oxide is the simplest thermally stable odd-electron molecule known and, accordingly, its electronic structure and reaction chemistry have been very extensively studied. The compound is an intermediate in the production of nitric acid and is prepared industrially by the catalytic oxidation of ammonia (p. 466). On the laboratory scale it can be synthesized from aqueous solution by the mild reduction of acidified nitrites with iodide or ferrocyanide or by the disproportionation of nitrous acid in the presence of dilute sulfuric acid ... 

Although most of the molecules and polyatomic ions referred to in general chemistry follow the octet rule, there are some familiar species that do not. Among these are molecules containing an odd number of valence electrons. Nitric oxide, NO, and nitrogen dioxide, N02, fall in this category ... 

Clarke Ml, Gaul JB (1993) Chemistry Relevant to the Biological Effects of Nitric Oxide and Metallonitrosyls. 81 147-181... 

Cueto, R. and Pryor, W.A. 1994. Cigarette smoke chemistry conversion of nitric oxide to nitrogen dioxide and reactions of nitrogen oxides with other smoke components as studied by fourier transform infrared... 

Butler, A. Rhodes, P. Nitric Oxide in Physiology and Medicine In Uses of Inorganic Chemistry in Medicine, Farrell, N., Ed. The Royal Society of Chemistry Cambridge, 1999, pp 58-76. 

Kopelman et al.73 have prepared fiber optic sensors that are selective for nitric oxide and do not respond to most potential interferents. Both micro-and nanosensors have been prepared, and their response is fast (<1 s), reversible, and linear up to 1 mM concentrations of nitric oxide. The respective "chemistry" at the fiber tip was contacted with the sample, light was guided to the sample through the microfiber, and emitted light was collected by a microscope (without the use of fibers, however). 

D. L. H. Williams Nitrosation Reactions and the Chemistry of Nitric Oxide , Elsevier, Amsterdam, 2004. 

S / V CONTENTS Preface, Robert W. Hay. Structure and Function of Manganese-Containing Biomolecules, David C. Weather-bum. Repertories of Metal Ions as Lewis Acid Catalysts in Organic Reactions, Junghan Suh. The Multicopper-Enzyme Ascorbate Oxidase, Albrecht Messerschmidt. The Bioinorganic Chemistry of Aluminum, Tomas Kiss and Etelka Farkas. The Role of Nitric Oxide in Animal Physiology, Anthony R. Butler, Frederick Flitney and Peter Rhodes. Index. 

Nitric oxide is important to a wide variety of mammalian physiological processes (1,2), beyond being a constituent of air pollution (3). Natural physiological activities are now known to include roles in blood pressure control, neurotransmission and immune response, and a number of disease states involving NO imbalances have been reported (2,4) as the result of extensive research activity into the chemistry, biology and pharmacology of NO. Understanding the fundamental reaction mechanisms... 

Redox reactions involving nitric oxide have important implications beyond their fundamental chemistry as demonstrated by the controversy in the biomedical literature regarding conditions under which generation of NO leads to the amelioration or the exacerbation of oxidative stress in mammalian systems (95). Oxidative stress is defined as a disturbance in the balance between production of reactive oxygen species (pro-oxidants) and antioxidant defenses (96). Reactive oxygen species include free radicals and peroxides as well as other reactants such as oxidative enzymes with metal ion sites in high oxidation states. The... 

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