Nitrendipine Cyclosporine

Rahn KH, Barenbrock M, Fritschka E, Heinecke A, Lippert J, Schroeder K, Hauser I, Wagner K, Neumayer HH. Effect of nitrendipine on renal function in renal-transplant patients treated with cyclosporin a randomised trial. Lancet 1999 354(9188) 1415-20. 

Clinically important, potentially hazardous interactions with aluminium hydroxide, antacids, charcoal, cholestyramine, colestimide, colestipol, cyclosporine, cytochrome P4503A substrates, dapsone, estrogenic hormones, nitrendipine, oral contraceptives... 

Phenytoin causes gingival hyperplasia, which occurs with much greater frequency in children (60%) than in adults (40%), shows no race or sex predilection, and may appear 2 to 3 months after the initiation of therapy. Gingival hyperplasia, which does not occur in the toothless portion of the gum, regresses gradually on discontinuation of the medication. Other medications causing gingival hyperplasia include cyclosporin, nifedipine, diltiazem, verapamil, and nitrendipine (see also Table 10). 

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