Nifedipine Sirolimus

Clinically important, potentially hazardous interactions with itraconazole, nifedipine, sirolimus... [Pg.381]

Monitor patients receiving sirolimus or nifedipine in combination with micafungin for sirolimus or nifedipine toxicity, and reduce sirolimus or nifedipine dosage if necessary. [Pg.1697]

Micafungin, anidulafungin Micafungin increases levels of nifedipine, cyclosporine, sirolimus anidulafungin is relatively free of this interaction ... [Pg.1063]

Clinically important, potentially hazardous interactions with abacavir, atorvastatin, bepridil, bupropion, carbamazepine, clarithromycin, cyclosporine, dexamethasone, digoxin, felodipine, fluticasone propionate, fosamprenavir, itraconazole, ketoconazole, lovastatin, methadone, midazolam, nicardipine, nifedipine, phenobarbital, phenytoin, rifabutin, simvastatin, sirolimus, St John s wort, systemic lidocaine, tacrolimus, tenofovir, trazodone, vinblastine, vincristine, voriconazole, warfarin, zidovudine... [Pg.345]

Diltiazem and verapamil raise sirolimus levels, and dosage adjustments may be necessaiy. Nicardipine is predicted to interact similarly. Nifedipine appears not to interact with sirolimus. [Pg.1072]

Nifedipine [which does not inhibit CYP3A4] is said not to interact, and a study comparing 16 patients taking nifedipine and sirolimus with 10 patients taking sirolimus alone found no significant differences in sirolimus pharmacokinetics between the two groups. ... [Pg.1072]

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