Prazosin Nifedipine

Also analyzed clonidine, diltiazem, metoprolol, nifedipine, prazosin, propranolol, verapamil... 

Kiss I, Farsang C. Nifedipine-prazosin interaction in patients with essential hypertension. 

Ditropan XL Procardia XL Glucotrol XL Alpress XL (France) Cardura XL (Germany) Concerta Covera HS DynaCirc CR Oxybutynin chloride Nifedipine Glipizide Prazosin Doxazosin mesylate Methylphenidate HC1 Verapamil HC1 Isradipine... 

An interaction of prazosin with nifedipine or verapamil resulted in acute hypotension (203,204). The mechanism appears to be partly kinetic (the systemic availability of prazosin increasing by 60%) and partly dynamic. 

Jee LD, Opie LH. Acute hypotensive response to nifedipine added to prazosin in treatment of hypertension. BMJ (Clin Res Ed) 1983 287(6404) 1514. 

Thaliporphine (0.1-100 pM), a potent vasoconstrictor, was observed to produce contractions in the isolated guinea-pig ileum in a concentration-dependent manner. These contractions were not affected by pretreatment of the ileum with tetrodotoxin, phentolamine, prazosin, propranolol, naloxone, atropine, diphenhydramine, methysergide, indomethacin or staurosporine. However, the contraction was markedly inhibited by nifedipine and verapamil, suggesting that thaliporphine produces intestinal smooth muscle contraction by a direct effect on muscle mediated by an increased Ca+2 influx through voltage-dependent Ca+2 channels [327]. 

Drugs or pharmacological interventions (heparin (Berger and Zaret 1984), antimicrobials or antibiotics, anticonvulsants, tranquilizers, anti-inflammatory agents (Chervu et al. 1981 Hladik et al. 1982), nifedipine (Sampson 1993), prazosin, digoxin (Lee 1983), propanolol, hydralazine, methyldopa, verapamil, chlorothiazide, furosemide, ranitidine, iron therapy, etoposide-h doxontbicin (Sampson 1993, 1995), others)... 

Also analyzed acebutolol, acepromazine, acetaminophen, acetazolamide, acetophenazine, albuterol, amitriptyline, amobarbital, amoxapine, antipsrrine, atenolol, atropine, azata-dine, baclofen, benzocaine, bromocriptine, brompheniramine, brotizolam, bupivacaine, buspirone, butabarbital, butalbital, caffeine, carbamazepine, cetirizine, chlorqyclizine, chlordiazepoxide, chlormezanone, chloroquine, chlorpheniramine, chlorpromazine, chlorpropamide, chlorprothixene, chlorthalidone, chlorzoxazone, cimetidine, cisapride, clomipramine, clonazepam, clonidine, clozapine, cocaine, codeine, colchicine, qyclizine, (yclo-benzaprine, dantrolene, desipramine, diazepam, diclofenac, diflunisal, diltiazem, diphenhydramine, diphenidol, dipheno late, dipyridamole, disopyramide, dobutamine, doxapram, doxepin, droperidol, encainide, ethidium bromide, ethopropazine, fenoprofen, fentanyl, flavoxate, fluoxetine, fluphenazine, flurazepam, flurbiprofen, fluvoxamine, fii-rosemide, glutethimide, glyburide, guaifenesin, haloperidol, homatropine, hydralazine, hydrochlorothiazide, hydrocodone, hydromorphone, hydro g chloroquine, hydroxyzine, ibuprofen, imipramine, indomethacin, ketoconazole, ketoprofen, ketorolac, labetalol, le-vorphanol, lidocaine, loratadine, lorazepam, lovastatin, loxapine, mazindol, mefenamic acid, meperidine, mephenytoin, mepivacaine, mesoridazine, metaproterenol, methadone, methdilazine, methocarbamol, methotrexate, methotrimeprazine, methoxamine, methyl-dopa, methylphenidate, metoclopramide, metolazone, metoprolol, metronidazole, midazolam, moclobemide, morphine, nadolol, nalbuphine, naloxone, naphazoline, naproxen, nifedipine, nizatidine, norepinephrine, nortriptyline, oxazepam, oxycodone, oxymetazo-line, paroxetine, pemoline, pentazocine, pentobarbital, pentoxifylline, perphenazine, pheniramine, phenobarbital, phenol, phenolphthalein, phentolamine, phenylbutazone, phenyltoloxamine, phenytoin, pimozide, pindolol, piroxicam, pramoxine, prazepam, prazosin, probenecid, procainamide, procaine, prochlorperazine, procyclidine, promazine, promethazine, propafenone, propantheline, propiomazine, propofol, propranolol, protriptyline, quazepam, quinidine, quinine, racemethorphan, ranitidine, remoxipride, risperidone, salicylic acid, scopolamine, secobarbital, sertraline, sotalol, spironolactone, sulfinpyrazone, sulindac, temazepam, terbutaline, terfenadine, tetracaine, theophylline, thiethyl-perazine, thiopental, thioridazine, thiothixene, timolol, tocainide, tolbutamide, tolmetin, trazodone, triamterene, triazolam, trifluoperazine, triflupromazine, trimeprazine, trimethoprim, trimipramine, verapamil, warfarin, xylometazoline, yohimbine, zopiclone... 

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