Nicotinic acid Inositol niacinate

The fat-soluble vitamins are A, D, E, and K. The water-soluble vitamins are thiamine (vitamin Bj), riboflavin, nicotinic acid (niacin) and nicotinamide, pyridoxine (vitamin B6), pantothenic acid, biotin, para-aminobenzoic acid, choline, inositol, and other lipotropic agents, ascorbic acid (vitamin C), the riboflavonoids, folate, and vitamin B12 (see Figure 66.1 and Figure 66.2, and Table 66.1). 

Inositol niacinate (inositol nicotinate hexanicoti-noyl cis-l,2,3,5-frans-4,6-cyclohexane myo-inositol hexa-3-pyridine-carboxylate) is a synthetic derivative of M., in which each hydroxyl group is esterified with a molecule of nicotinic acid it causes peripheral vasodilation and is used clinically for the symptomatic relief of severe intermittent claudication and Raynaud s phenomenon. 

The large amounts of water which pass through most animals daily tend to carry out the water-soluble vitamins of the body, thereby depleting the supply. Thus, they must be supplied in the diet on a day-to-day basis. The water-soluble vitamins are vitamin C (ascorbic acid), B-1 (thiamin), B-2 (riboflavin), B-6 (pyridoxine), niacin (nicotinic acid), pantothenic acid, biotin, folic acid (folacin), choline, B-12, and inositol. 

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