Nichols, David

Thanks go to Dr. Michael McKee at Auburn University and the Alabama Research and Education Network, both of which allowed software to be tested on their computers. Thanks are also due the Nichols Research Corporation and Computer Sciences Corporation and particularly Scott von Laven and David Ivey for being so tolerant of employees engaged in such job-related extracurricular activities. 

Michael Janusa Nicholls State University J. David Jenkins Georgia Southern University... 

David Edgren Harold Leeper Kirstin Nichols Jeremy Wright ALZA Corporation... 

Larry L. Augsburger University of Maryland Baltimore, Maryland David E. Nichols Purdue University West Lafayette, Indiana... 

Finally, I thank the wonderful scientists with whom I have collaborated on the research leading to this book Guy Sapirstein, Thomas Moore, Alan Scoboria, Blair Johnson, Brett Deacon, Tania Huedo-Medina, Joanna Moncrieff, Corrado Barbui, Andrea Cipriani, Sarah Nicholls and David Antonuccio. Research is a team effort, and these colleagues have made wonderful teams. 

Walter Gorn Old (Sepharial) The New Manual of Astrology (London Nichols, 1909) Prognostic Astronomy (London L. N. Fowler, 1901) Eclipses (London L. N. Fowler, 1915) The Book of the Simple Way of Laotze (London Philip Wellby, 1904 Rider, 1913 Philadelphia David McKay, 1915) Shu Link or the Chinese Historical Classic, trans. Old (London Theosophical Publishing... 

David E. Nichols and Richard A. Glennon 143 Common Neurochemical Correlates to the Action of Hallucinogens Michel Hamon... 

David E. Nichols, Robert Oberlender, and Dennis J. McKenna. "Stereochemical Aspects of Hallucinogenesis." In Biochemistry and Physiology of Substance Abuse, vol. Ill, edited by R. R. Watson, pp. 1-39. Boca Raton, FL CRC Press, 1991. 

Dennis J. McKenna, Adil J. Nazarali, Andrew J. Hoffman, David E. Nichols, C. A. Mathis, and Juan M. Saavedra. "Common receptors for hallucinogens in rat brain a comparative autora-diographic study using [125IJLSD and [125IJ-DOI, a new psychotomimetic radioligand." Brain Research 476 (1989) 45-56. 

Completely unknown. Salvia divinorum represents an entirely new class of entheogen. A Novascreen receptor site screening sponsored by David Nichols discovered no binding Inhibition for the forty reference compounds tested, covering all major known receptors. 

I am grateful to Dr Leander Valdes III for supplying a reference sample of salvinorin A, and Dr David Nichols for his role in the receptor site screening of salvinorin A through his NIMH-funded research program. 

David E. Nichols Purdue University West Lafayette, Indiana... 

Figure 30-13 Section through a rat brain. This brain, which has been very widely used in neurochemical studies, appears superficially to be quite different from the human brain (Fig. 30-1), which is characterized by its large cerebral cortex. However, basic pathways are the same. Some major pathways for glutamate-secreting (glutamatergic) neurons are marked by arrows. Most of these originate in the neocortex (outer layers of the cerebral cortex) and the hippocampus. From Nicholls.149 Courtesy of David G. Nicholls.

Shortly after discovering salvinorin A s effects, Siebert sent a sample to David Nichols who initiated a NovaScreenTM receptor site screening. The screening results were in contrast to those of all previously tested psychedelics. Salvinorin A did not affect any of the receptor sites tested, which included all of the likely known receptor sites for other psychedelics. 

Bruce S. Dien, 1 Nick Nagle,2 Kevin B. Hicks,3 Vijay Singh,4 Robert A. Moreau,3 Melvin P. Tucker,2 Nancy N. Nichols,1 David B. Johnston,3 Michael A. Cotta,1 Quang Nguyen,2 and Rodney J. Bothast5... 

David E. Nichols, Ph.D., is Professor of Medicinal Chemistry and Molecular Pharmacology at Purdue University. He has over 230 published research reports, book chapters, and symposia proceedings, and six U.S. patents. In 1993, he was the lead founder of the Heffter Research Institute (www.heffter.org), a nonprofit institute to support research into the scientific and medical value of hallucinogens. He can be contacted at drdave pharmacy.purdue.edu. 

RICHARD J. NICHOLS, WOLFGANG HAISS, DAVID G. FERNIG HARM VAN ZALINGE, DAVID J. SCHIFFRIN, AND JENS ULSTRUP ... 

MTA was first produced in 1992. Developed by Purdue University chemistry professor David Nichols,... 

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