Niacin adverse reaction

Some combinations of lipid-altering drugs are currently available such as extended-release niacin/lovastatin and ezetimibe/simvastatin, which are more promising for lipid-lowering therapy with stronger effects and decreased adverse reactions. 

Adverse reactions Thiamine rare anaphylaxis after a large IV dose Riboflavin none known Niacin or nicotinic acid Cardiac arrythmias may occur rarely Pyridoxine Lxmg-term megadoses may produce sensory neuropathy... 

Niacin has many common adverse drug reactions most of the symptoms and biochemical abnormalities seen do not require discontinuation of therapy. 

Acipimox is not associated with liver adverse drug reactions and should be safe to use. Niacin (nicotinic acid) has been reported to cause transient elevation in transaminases at high doses, as well as more serious... 

Allergic skin reactions (17) and other adverse effects, including dermatological problems and neurological symptoms, have been described in individuals using such formulations. Heavy chronic consumption of kava-kava can lead to a pellagroid dermopathy that appears to be unrelated to niacin deficiency (18). 

---